Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077098PMC
http://dx.doi.org/10.3324/haematol.2014.104703DOI Listing

Publication Analysis

Top Keywords

red blood
4
blood cell
4
cell immunization
4
immunization sickle
4
sickle cell
4
cell disease
4
disease evidence
4
evidence large
4
large responder
4
responder group
4

Similar Publications

Variations and Opportunities in Postnatal Management of Hemolytic Disease of the Fetus and Newborn.

JAMA Netw Open

January 2025

Division of Neonatology, Department of Pediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, the Netherlands.

Importance: Preventive efforts in pregnancy-related alloimmunization have considerably decreased the prevalence of hemolytic disease of the fetus and newborn (HDFN). International studies are therefore essential to obtain a deeper understanding of the postnatal management and outcomes of HDFN. Taken together with numerous treatment options, large practice variations among centers may exist.

View Article and Find Full Text PDF

Therapeutic Potential of Carbon Dots Derived from Phytochemicals as Nanozymes Exhibiting Superoxide Dismutase Activity for Anemia.

ACS Appl Mater Interfaces

January 2025

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

Anemia is a potentially life-threatening blood disorder caused by an insufficient erythroblast volume in the circulatory system. Self-renewal failure of erythroblast progenitors is one of the key pathological factors leading to erythroblast deficiency. However, there are currently no effective drugs that selectively target this process.

View Article and Find Full Text PDF

The underlying mechanisms explaining the differential course of SARS-CoV-2 infection and the potential clinical consequences after COVID-19 resolution have not been fully elucidated. As a dysregulated mitochondrial activity could impair the immune response, we explored long-lasting changes in mitochondrial functionality, circulating cytokine levels, and metabolomic profiles of infected individuals after symptoms resolution, to evaluate whether a complete recovery could be achieved. Results of this pilot study evidenced that different parameters of aerobic respiration in lymphocytes of individuals recuperated from a severe course lagged behind those shown upon mild COVID-19 recovery, in basal conditions and after simulated reinfection, and they also showed altered glycolytic capacity.

View Article and Find Full Text PDF

Induction of Erythropoietin by dietary Medium-Chain Triacylglycerol in Humans.

Am J Physiol Endocrinol Metab

January 2025

The August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.

Erythropoietin (EPO) is pivotal in regulating red blood cell (erythrocyte) concentrations and is primarily synthesized in the kidney. Recent research has unveiled a possible link between elevated circulating concentrations of ketone bodies (KB) and circulating EPO concentrations, however, it is not known whether nutritionally induced endogenous ketogenesis can be a stimulus to induce EPO in humans. Therefore, this study aimed to assess whether acute and chronic intake of medium-chain fatty acid (MCFA)-containing triacylglycerol (MCT), which rapidly enhances endogenous circulating KB, would elevate circulating EPO concentrations in humans, as indicated by prior work with exogenous KB administration.

View Article and Find Full Text PDF

A Novel Hollow Core Antiresonant Fiber-Based Biosensor for Blood Component Detection in the THz Regime.

Biomed Phys Eng Express

January 2025

Electronics and Communication Engineering, SRM Institute of Science and Technology (Deemed to be University), Tech Park, SRM Nagar, Kattankulathur, Kattankulathur, Tamilnadu, 603203, INDIA.

This article proposes a novel biosensor based on a five-semi-circular cladding tube hollow core antiresonant fiber (HC-ARF) with a frequency range of 0.5-2.8 THz, using Zeonex as the background material.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!