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| http://dx.doi.org/10.1016/S0140-6736(14)60637-1 | DOI Listing |
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Age- and sex-specific incidence rates and future projections for hip fractures in Zimbabwe.
BMJ Glob Health
January 2025
University of Bristol Musculoskeletal Research Unit, Bristol, Bristol, UK.
Introduction: Population ageing in Africa is increasing healthcare demands. Hip fractures require multidisciplinary care and are considered an indicator condition for age-related health services. We aimed to estimate current hip fracture incidence in Zimbabwe, compare rates against other regional estimates and estimate future fracture numbers.
View Article and Find Full Text PDFThe Application of Machine Learning Algorithms to Predict HIV Testing in Repeated Adult Population-Based Surveys in South Africa: Protocol for a Multiwave Cross-Sectional Analysis.
JMIR Res Protoc
January 2025
South African Medical Research Council/University of Johannesburg Pan African Centre for Epidemics Research Extramural Unit, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.
Background: HIV testing is the cornerstone of HIV prevention and a pivotal step in realizing the Joint United Nations Program on HIV/AIDS (UNAIDS) goal of ending AIDS by 2030. Despite the availability of relevant survey data, there exists a research gap in using machine learning (ML) to analyze and predict HIV testing among adults in South Africa. Further investigation is needed to bridge this knowledge gap and inform evidence-based interventions to improve HIV testing.
View Article and Find Full Text PDFAnterior segment dysgenesis (ASD) defines a collection of congenital eye disorders that affect structures within the anterior segment of the eye. Mutations in genes that initiate and regulate the complex pathways involved in eye development can cause a spectrum of disorders such as ASD, congenital cataracts and corneal opacity. In South Africa, causes of ASD are poorly understood with few studies looking at the possible genetic basis for these disorders.
View Article and Find Full Text PDFNew evidence for early Indian Ocean trade routes into the South African interior.
Proc Natl Acad Sci U S A
February 2025
Cultural Heritage Unit, Conservation Services Division, South African National Parks, Pretoria 0002, South Africa.
The rise and spread of ancient Indian Ocean Rim (IOR) trade networks profoundly impacted southern Africa. Control over this trade played a critical role in the rise and maintenance of complex societies of the second millennium CE such as Mapungubwe and Great Zimbabwe. While the African origins of this trade lie in the first millennium CE, understanding its earliest phases and subsequent development in the far south has been hampered by a general paucity of research.
View Article and Find Full Text PDFStrength of Genetic Associations with Thyrotropin Values Differs Between Populations with Similarity to African and European Reference Populations.
Thyroid
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Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Epidemiological data suggest the population distribution of thyrotropin (TSH) values is shifted toward lower values in self-identified Black non-Hispanic individuals compared with self-identified White non-Hispanic individuals. It is unknown whether genetic differences between individuals with genetic similarities to African reference populations (GSA) and those with similarities to European reference populations (GSE) contribute to these observed differences. We aimed to compare genome-wide associations with TSH and putative causal TSH-associated variants between GSA and GSE groups.
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