AI Article Synopsis

  • The study evaluated the effectiveness of household bleach, a sodium dichloroisocyanurate (NaDCC)-based disinfectant, and an eco-friendly cleaning agent (EFCA) on different strains of Staphylococcus aureus.
  • Both bleach and NaDCC showed significant reduction of bacteria in suspension tests, but were less effective on surfaces, with bleach effectively eliminating specific biofilms only at high concentrations.
  • The eco-friendly cleaning agent did not show any antimicrobial activity, raising concerns about the practical effectiveness of the disinfectants at recommended use dilutions, especially regarding biofilm eradication.

Article Abstract

The aim of this study was to determine the effect of household bleach, a sodium dichloroisocyanurate (NaDCC)-based disinfectant and an eco-friendly cleaning agent (EFCA) on four Staphylococcus aureus strains, including two isolated from community infections. The products were assessed using the suspension (EN 1276) and surface (EN 13697) tests, while biofilm activity was determined using the 96-well plate method. Bleach and NaDCC caused > 5 log reduction in viable counts within 5 min in suspension, whilst on surfaces the reduction was < 3 log. Bleach at 5000 ppm free available chlorine completely eradicated MSSA NCTC 13297 and PVL CA MSSA biofilms within 10 min, but not at 500 and 50 ppm, NaDCC was less effective against biofilms. The EFCA demonstrated no antimicrobial activity. It is of concern that at the recommended "use" dilution, bleach did not eradicate biofilms. Although increasing contact time and/or concentration should improve the activity, this may not be acceptable to the user.

Download full-text PDF

Source
http://dx.doi.org/10.1080/09603123.2014.903905DOI Listing

Publication Analysis

Top Keywords

staphylococcus aureus
8
cleaning agent
8
comparison sensitivity
4
sensitivity staphylococcus
4
aureus isolates
4
isolates chlorine-based
4
chlorine-based disinfectants
4
disinfectants eco-friendly
4
eco-friendly commercially
4
commercially cleaning
4

Similar Publications

Background: Polymethylmethacrylate (PMMA) antibiotic-laden bone cement (ALBC) is commonly used in total joint arthroplasty to treat and potentially prevent prosthetic joint infection (PJI). Multiple properties impact the elution characteristics of antibiotics from PMMA-based ALBC, including viscosity. What is not known is how medium-viscosity cement formulations affect antibiotic elution and how different cement products from different manufacturers compare regarding reaching the minimum inhibitory concentration (MIC) of antibiotics for common PJI-causing organisms in an in vitro setting.

View Article and Find Full Text PDF

Objective: The purpose of this study was to describe the safety and efficacy of percutaneous drain placement for postoperative fluid collections in the breast.

Methods: A retrospective review was conducted of the patient characteristics, intervention data, and clinical outcomes of the 43 adult patients who underwent percutaneous drain placement for fluid collections at a tertiary care hospital over a 13-year period ending February 28, 2023.

Results: Most fluid collections treated with percutaneous drain placement were secondary to ipsilateral breast surgery (92%, 44/48), most commonly breast reduction (23%, 10/44) and mastectomy with immediate tissue expander reconstruction (16%, 7/44).

View Article and Find Full Text PDF

Characterization and bioinformatic analysis of a new chimeric endolysin against MRSA with great stability.

AMB Express

December 2024

Department of Biotechnology, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran.

Antibiotics become less effective in treating infectious diseases as resistance increases. Staphylococcus aureus is a global problem due to its ability to form biofilms and resistance mechanisms. Phage endolysin is one of the most promising methods for combating antibiotic resistance.

View Article and Find Full Text PDF

Sauerkraut contains various fermentative microorganisms that produce active metabolites, enhancing immunity and resistance to infections. However, its effects on methicillin-resistant (MRSA)-induced acute lung injury (ALI) remain unclear. Using RAW264.

View Article and Find Full Text PDF

Stubborn biofilm infections pose serious threats to public health. Clinical practices highly rely on mechanical debridement and antibiotics, which often fail and lead to persistent and recurrent infections. The main culprits are 1) persistent bacteria reviving, colonizing, and rejuvenating biofilms, and 2) secondary pathogen exposure, particularly in individuals with chronic diseases.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!