Atypical femur fractures were first reported in 2007 and are now recognized as a unique clinical entity. They occur along the shaft of the femur extending from the subtrochanteric region proximally to the distal femoral metaphysis. These fractures have an increased incidence in patients taking bisphosphonates for osteoporosis and develop as stress reactions in the lateral cortex of the femoral shaft. The fractures often have a distinct radiographic appearance with thickening or beaking of the lateral cortex. Treatment should be initiated immediately. There is a higher incidence of complications with atypical fractures. Early detection of these fractures can greatly reduce morbidity.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.cger.2014.01.010 | DOI Listing |
Skeletal Radiol
December 2024
Department of Orthopedic Surgery, Akita Hospital, 2-6-12 Takara, Chiryu City, Aichi, 472-0056, Japan.
Objective: To determine which parameters, including femur morphology, proximal femur bone mineral density, or patient characteristics, are associated with bisphosphonate-related atypical femur fractures (AFFs) and to investigate the relationships between AFF location and these parameters.
Materials And Methods: Sixteen females with a history of bisphosphonate use who presented with AFFs and 38 females without AFFs, even those with long-term bisphosphonate use of > 5 years, were compared. Patient characteristics; physique, gait ability, and history of pain and medication, were recorded.
Cureus
November 2024
Internal Medicine, Centro Hospitalar Tondela Viseu, Viseu, PRT.
Mesenchymal chondrosarcoma (MCS) is a rare, aggressive subtype of chondrosarcoma characterized by biphasic histology, often misdiagnosed due to its rarity and histological resemblance to other small round cell tumors. It predominantly affects adolescents and young adults. We report a 27-year-old male presenting with a progressively enlarging, painless mass in the right inframammary region, initially attributed to muscular strain.
View Article and Find Full Text PDFJ Bone Miner Res
December 2024
Calcium Metabolism and Osteoporosis Program, WHO Collaborating Centre for Metabolic Bone Disorders, American University of Beirut Medical Centre, Beirut, Lebanon.
Atypical femur fractures (AFFs) have been reported with long term use of anti-resorptive drugs. Early identification is crucial because it allows early intervention to stop the progression to complete fracture, thus potentially reducing the ensuing burden. It has been shown that extending the scan image to take a full-length image of the femur (FFI) using single energy (SE) X-rays at the time of a dual-energy X-ray absorptiometry (DXA) scan can detect findings in the spectrum of AFF.
View Article and Find Full Text PDFRadiol Case Rep
February 2025
Radiology, Medical Fitness/Dubai Academic Health Corporation, Dubai, United Arab Emirates.
Cortical desmoid is an uncommon benign bony lesion that can typically be diagnosed through conventional radiographic methods. However, here we present an atypical case of a 14-year-old male who presented with a history of trauma, and the initial X-ray showed a right femur suspicious bony lesion. Still, the subsequent use of CT and MRI confirmed the diagnosis of cortical desmoid, so conservative management and follow-up imaging was recommended.
View Article and Find Full Text PDFMedicine (Baltimore)
December 2024
The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoinflammatory disorder that commonly poses diagnostic challenges due to its atypical symptomatology. This observational study aimed to investigate the clinical features, laboratory test results, imaging features, and treatment strategies for pediatric patients with CRMO. We retrospectively analyzed 7 pediatric patients with CRMO treated at the Department of Pediatric Orthopedics, First Affiliated Hospital of Guangzhou University of Chinese Medicine between January 2018 and February 2022.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!