[Interrelation of changes in the levels of calcium, calmodulin and cyclic nucleotides in children with ectopic types of arrhythmia].

In 61 children with different patterns of ectopic arrhythmias (premature heart beat, paroxysmal and non-paroxysmal tachycardia), the peripheral blood leukocytes and myocardial tissues were examined for the content of calmodulin (CM), ionized calcium (Ca2+) and cyclic nucleotides (CN). The data obtained indicate that the CM-Ca2+ and CN system are involved in the genesis of arrhythmias in children and may be used as additional criteria in the diagnosis of cardiac rhythm abnormalities.