Traumatic brain injury due to primary blast loading has become a signature injury in recent military conflicts. Efforts have been made to study the stress wave propagation in the head. However, the relationship of incident pressure, reflected pressure and intracranial pressure is still not clear, and the experimental findings reported in the literature are contradictory. In this article, an analytical model is developed to calculate the stress wave transfer through a multiple-layered structure which is used to mimic the head. The model predicts stress at the scalp-skull and skull-brain interfaces as the functions of reflected pressure, which is further dependent on incident pressure. A numerical model is used to corroborate the theoretical predictions. It is concluded that scalp has an amplification effect on intracranial pressure. If scalp is absent, there exists a critical incident pressure, defined as P at approximately 16 kPa. When peak incident pressure σ is higher than 16 kPa, the pressure at the skull-brain interface is greater than σ ; otherwise, it is lower than σ .
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http://dx.doi.org/10.1177/0954411914530882 | DOI Listing |
Curr Cardiol Rep
January 2025
John Ochsner Heart and Vascular Institute, Ochsner Clinical School University of Queensland School of Medicine, New Orleans, LA, USA.
Purpose Of Review: To provide a narrative overview of trends and disparities in the cardiometabolic profiles of U.S. adults by synthesizing findings from nationally representative studies conducted between 1999 and 2020.
View Article and Find Full Text PDFMagnes Res
January 2025
Department of Anaesthesiology & Pain Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Korea, Department of Anaesthesiology & Pain Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.
Although intraoperative magnesium sulphate administration has various advantages, its influence on the occurrence of postoperative acute kidney injury (AKI) remains unclear, particularly in patients undergoing robot-assisted radical prostatectomy (RARP). The steep Trendelenburg position and a high intra-abdominal pressure can render patients susceptible to AKI after surgery. This study aimed to evaluate the effects of intraoperative magnesium sulphate administration on postoperative AKI in patients who underwent RARP.
View Article and Find Full Text PDFESC Heart Fail
January 2025
Division of Cardiology, Department of Medicine, Kindai University Faculty of Medicine, Osaka, Japan.
Aims: The Tpeak-Tend interval on electrocardiogram may be a predictor of worse outcomes in Takotsubo syndrome (TTS), but the mechanisms have not been fully determined. This study aimed to investigate the relationships between the corrected Tpeak-Tend (cTp-e) interval and coronary microvascular-dysfunction (CMD) assessed by the angiography-derived index of microvascular resistance (Angio-IMR) and the in-hospital prognosis in patients with TTS.
Methods And Results: We retrospectively evaluated 111 consecutive patients admitted for TTS who underwent coronary angiography at Kindai University Hospital from October 2009 to July 2023.
J Am Heart Assoc
January 2025
Department of Medicine, Division of Cardiology Emory University School of Medicine Atlanta GA USA.
Background: Acute psychological stress may induce physiological changes predisposing individuals to adverse health outcomes through hemodynamic and vascular effects. We studied the association between the aggregated stress-induced changes in hemodynamic and vascular function tests with adverse cardiovascular outcomes in patients with coronary artery disease, after adjusting for sociodemographic and clinical factors.
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J Pain Res
January 2025
Department of Anesthesiology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250033, People's Republic of China.
Background: Postoperative sore throat (POST) is a significant adverse effect after endotracheal intubation, especially with double-lumen endotracheal tubes (DLTs). Ultrasound-guided internal branch of the superior laryngeal nerve block (US-guided iSLNB) presents a potential intervention for POST. In this first randomized controlled trial to date, we aimed to investigate the effects of US-guided iSLNB, with or without perineural dexmedetomidine, on the incidence and severity of POST following DLTs.
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