Systematic study of Yb doping concentration in the Yb:YLF cryocoolers by means of optical and mass spectroscopies has identified iron ions as the main source of the background absorption. Parasitic absorption was observed to decrease with Yb doping, resulting in optical cooling of a 10% Yb:YLF sample to 114K ± 1K, with room temperature cooling power of 750 mW and calculated minimum achievable temperature of 93 K.

Download full-text PDF

Source
http://dx.doi.org/10.1364/OE.22.007756DOI Listing

Publication Analysis

Top Keywords

identification parasitic
4
parasitic losses
4
losses ybylf
4
ybylf prospects
4
prospects optical
4
optical refrigeration
4
refrigeration 80k
4
80k systematic
4
systematic study
4
study doping
4

Similar Publications

Ticks continue to invade new regions spreading pathogens of zoonotic and veterinary importance. Diverse tick species have been reported in Ghana due to the continuous trade of livestock. In this study, ticks were collected from cattle in three sites within Southern Ghana.

View Article and Find Full Text PDF

Circulating sexual stages of ) can be transmitted from humans to mosquitoes, thereby furthering the spread of malaria in the population. It is well established that antibodies can efficiently block parasite transmission. In search for naturally acquired antibodies targets on sexual stages, we established an efficient method for target-agnostic single B cell activation followed by high-throughput selection of human monoclonal antibodies (mAbs) reactive to sexual stages of in the form of gametes and gametocyte extracts.

View Article and Find Full Text PDF

Purification and transcriptomic characterization of proliferative cells of selectively affected by irradiation.

Front Parasitol

March 2024

Departamento de Genética, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.

Flatworms depend on stem cells for continued tissue growth and renewal during their life cycles, making these cells valuable drug targets. While neoblasts are extensively characterized in the free-living planarian , and similar stem cells have been characterized in the trematode , their identification and characterization in cestodes is just emerging. Since stem cells are generally affected by irradiation, in this work we used this experimental approach to study the stem cells of the model cestode .

View Article and Find Full Text PDF

Introduction: Schistosomiasis has for many years relied on a single drug, praziquantel (PZQ) for treatment of the disease. Immense efforts have been invested in the discovery of protein kinase (PK) inhibitors; however, given that the majority of PKs are still not targeted by an inhibitor with a useful level of selectivity, there is a compelling need to expand the chemical space available for synthesizing new, potent, and selective PK inhibitors. Small-molecule inhibitors targeting the ATP pocket of the catalytic domain of PKs have the potential to become drugs devoid of (major) side effects, particularly if they bind selectively.

View Article and Find Full Text PDF

Introduction: Schistosomiasis (Bilharzia), a neglected tropical disease caused by parasites, afflicts over 240 million people globally, disproportionately impacting Sub-Saharan Africa. Current diagnostic tests, despite their utility, suffer from limitations like low sensitivity. Polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) remain the most common and sensitive nucleic acid amplification tests.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!