AI Article Synopsis
- We are examining spectroscopic devices for measuring cervical tissue to identify pre-cancerous and cancerous lesions.
- Despite having the same design, the devices showed consistent differences in their measurements.
- We developed a statistical model to identify and correct the sources of variability, aiming to enhance the accuracy and reliability of future tissue measurements.
Article Abstract
We are investigating spectroscopic devices designed to make in vivo cervical tissue measurements to detect pre-cancerous and cancerous lesions. All devices have the same design and ideally should record identical measurements. However, we observed consistent differences among them. An experiment was designed to study the sources of variation in the measurements recorded. Here we present a log additive statistical model that incorporates the sources of variability we identified. Based on this model, we estimated correction factors from the experimental data needed to eliminate the inter-device variability and other sources of variation. These correction factors are intended to improve the accuracy and repeatability of such devices when making future measurements on patient tissue.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083050 | PMC |
| http://dx.doi.org/10.1364/OE.22.007617 | DOI Listing |
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