We present a 60 years old male with transitional cell carcinoma of the left ureter. The right kidney was non excretory while the left one was the solitary functioning kidney with multiple renal cysts. He had presented with significantly deranged renal profile and left obstructed ureter. The ureterorenoscope could not be negotiated so exploration of the left ureter was done. This showed a growth in left ureter, confirmed as transitional cell carcinoma (TCC) on histopathology. Subsequently excision of the distal left ureter along with the tumour and the cuff of bladder (segmental ureterectomy) was contemplated. Proximally transureteroureterostomy was performed. Postoperative recovery was smooth and the renal profile became normal within 3 months.
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