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| http://dx.doi.org/10.7861/clinmedicine.14-2-196 | DOI Listing |
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Assessment of upper GI motor activity and GI symptoms in patients with amyotrophic lateral sclerosis: an observational study.
Front Neurol
January 2025
Department of Human Neurosciences, Sapienza University, Rome, Italy.
Background/aims: Oro-pharyngeal dysfunction has been reported in Amyotrophic Lateral Sclerosis (ALS). We aimed to assess ALS patients upper gastrointestinal (GI) motor activity and GI symptoms according to bulbar and spinal onset and severity of ALS.
Methods: ALS bulbar (B) and spinal (S) patients with ALS Functional Rating Scale (ALSFRS-r) ≥35, bulbar sub-score ≥10, and Forced Vital Capacity (FVC) >50%, underwent to: Fiberoptic Endoscopic Evaluation of Swallowing (FEES); esophageal manometry; gastric emptying; Rome symptom questionnaire.
A prospective study of diagnostic testing and hospital charges after brief resolved unexplained event.
J Pediatr Gastroenterol Nutr
January 2025
Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Massachusetts, USA.
Objectives: To evaluate diagnostic testing frequency/yield and determine drivers of hospital charges in a prospective cohort of infants with brief resolved unexplained event (BRUE) to test the hypothesis that length of stay (LOS), low-yield diagnostic testing, and repeat hospital visits increase costs.
Methods: We conducted a prospective cohort study of infants admitted after BRUE to determine how clinical practice impacts the cost of care. Charge data from our institution's billing records database included room and board, diagnostics, medications, and professional fees for index hospitalizations and 6-month follow-ups.
Improved Visualization of Oropharyngeal Tumors Using Simple Maneuvers During Flexible Endoscopy.
Ann Otol Rhinol Laryngol
January 2025
Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Objectives: To describe patient positioning maneuvers that optimize visualization of the oropharynx during flexible endoscopy.
Methods: An institutional database of videos obtained from 2021 to 2023 during flexible endoscopy of patients with oropharyngeal carcinoma (OPC) was reviewed. Patients seen outside the specialty head and neck clinic, those with tonsillar primary tumors, and those only with videos of fiberoptic swallowing evaluations were excluded.
Spatio-temporal segregation between sensory relay and swallowing pre-motor population activities by optical imaging in the rat nucleus of the solitary tract.
Pflugers Arch
January 2025
Division of Neurophysiology, Department of Physiology, Hyogo Medical University, Hyogo, 663 8501, Japan.
The nucleus tractus solitarius (NTS) contains neurons that relay sensory swallowing commands information from the oropharyngeal cavity and swallowing premotor neurons of the dorsal swallowing group (DSG). However, the spatio-temporal dynamics of the interplay between the sensory relay and the DSG is not well understood. Here, we employed fluorescence imaging after microinjection of the calcium indicator into the NTS in an arterially perfused brainstem preparation of rat (n = 8) to investigate neuronal population activity in the NTS in response to superior laryngeal nerve (SLN) stimulation.
View Article and Find Full Text PDFRisk factors and prognosis analysis of dysphagia after occipitocervical fusion surgery: a retrospective study of 43 cases.
J Orthop Surg Res
January 2025
Department of Spine Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350004, China.
Objectives: To analyze the risk factors for developing dysphagia after occipitocervical fusion (OCF) and investigate possible mechanisms and prognosis.
Methods: The case data of 43 patients who underwent OCF were retrospectively reviewed. Patients were divided into group A (dysphagia group) and group B (non-dysphagia group) based on Bazaz scoring criteria.
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