The patient is an obese, 55-year-old woman. She noticed purpura at several sites when she was 49 years old. She visited our clinic with a chief complaint of exertional dyspnea at 51 years of age. Physical examination revealed localized edema in the left chest wall and lower abdomen with translucent papules in the center. Macroglossia, hemorrhagic macules, loss of axillary and pubic hairs, and goose-egg sized swellings of submaxillary lymph nodes were also found. Laboratory data were within the normal range except an increase of IgD and low ECG voltage. Bone-marrow puncture revealed an increase (27%) of plasma cells with some atypicality. Serum immunoelectrophoresis clarified IgD lambda-type paraproteinemia and lambda-type Bence Jones proteinemia. Histologically, edema with an increase in GAG was conspicuous in the circumscribed areas of the middle dermis. Amyloid deposition was clarified in the walls of arterioles in the deep dermis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1346-8138.1989.tb01221.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Efficacy and adverse reactions of fractional CO2 lasers for treating papular acne scars: a retrospective study of 35 patients.
Lasers Med Sci
September 2024
Department of Dermatology, Qingdao Municipal Hospital&Qingdao Hospital, University of Health and Rehabilitation Sciences(Qingdao Municipal Hospital), Qingdao, Shandong, China.
Article Synopsis
- Papular acne scars are a common yet often overlooked type of acne scar, with our study identifying a prevalence of 34.6% among 370 patients at a Dermatology Laser Clinic.
- We analyzed the effectiveness of fractional CO2 laser treatment on these scars, where 35 patients received three sessions of the treatment over two months.
- Results showed significant improvement in scar assessments and patient satisfaction, highlighting the effectiveness of CO laser therapy for papular acne scars.
Localized Bullous Pemphigoid in a Patient with Acquired Reactive Perforating Collagenosis.
Case Rep Dermatol
January 2023
Department of Dermatology, Kita-Harima Medical Center, Ono City, Japan.
A 61-year-old man presented with 6-month and 5-day histories of multiple, pruritic nodular eruptions on the trunk and extremities and bullous eruptions on the left foot, respectively. The nodular eruptions had been treated with topical corticosteroids without improvement. He had been diagnosed with diabetes mellitus at the age of 42 years and had been suffering from end-stage renal disease for 1 year.
View Article and Find Full Text PDFHistopathological Study of Skin Lesions in a Tertiary Care Hospital: A Descriptive Cross-sectional Study.
JNMA J Nepal Med Assoc
April 2020
Department of Pathology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.
Introduction: Skin diseases are much common in developing countries. The spectrum varies according to geographic distribution, gender, age, and coexisting disorder. We conducted this study to find out the prevalence of different skin lesions and to evaluate their frequency and site of distribution.
View Article and Find Full Text PDFSkin and gastrointestinal symptoms in COVID-19.
Prz Gastroenterol
December 2020
Dermatology Department, Centre of Postgraduate Medical Education/Central Clinical Hospital of the Ministry of the Interior and Administration, Warsaw, Poland.
Introduction: The first cases of coronavirus disease 2019 (COVID-19) were noted in December 2019 in Wuhan province, China. The World Health Organisation (WHO) announced the pandemic status on March 11, 2020. The manifestations of the disease are as follows: fever, cough, fatigue, anosmia and ageusia, dyspnoea, chest pain, muscle soreness, chills, sore throat, rhinitis, headache, gastrointestinal (GI) symptoms, and dermal lesions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!