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http://dx.doi.org/10.4103/0019-5049.126854 | DOI Listing |
J Am Chem Soc
January 2025
Department of Chemistry, University of California Davis, Davis, California 95616, United States.
[FeFe]-hydrogenases are enzymes that catalyze the redox interconversion of H and H using a six-iron active site, known as the H-cluster, which consists of a structurally unique [2Fe] subcluster linked to a [4Fe-4S] subcluster. A set of enzymes, HydG, HydE, and HydF, are responsible for the biosynthesis of the [2Fe] subcluster. Among them, it is well established that HydG cleaves tyrosine into CO and CN and forms a mononuclear [Fe(II)(Cys)(CO)(CN)] complex.
View Article and Find Full Text PDFCureus
December 2024
Department of Surgery, Vardhman Mahavir Medical College (VMMC) & Safdarjung Hospital, New Delhi, IND.
Ectopic breast tissue (EBT) represents a congenital anomaly caused by incomplete regression of mammary ridges at the time of embryonic development. Typically, EBT presents along the mammary line, although usually in the axillary region, it has been located occasionally in unusual sites such as the vulva. Though relatively rare, it is generally subject to a wide range of pathologies that afflict normal breast tissue, encompassing both benign and malignant transformations.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Center for Sustainable Catalysis and Engineering, KU Leuven, Celestijnenlaan 200F, Leuven 3001, Belgium.
The local environment of the active site, such as the confinement of hydronium ions within zeolite pores, significantly influences catalytic turnover, similar to enzyme functionality. This study explores these effects in the hydrolysis of guaiacols─lignin-derived compounds─over zeolites in water. In addition to the interesting catechol products, this reaction is advantageous for study due to its bimolecular hydrolysis pathway, which involves a single energy barrier and no intermediates, simplifying kinetic studies and result interpretation.
View Article and Find Full Text PDFGenet Mol Biol
January 2025
Instituto Nacional de Pesquisas da Amazônia, Programa de Pós-Graduação em Genética, Conservação e Biologia Evolutiva (PPG GCBEv), Manaus, AM, Brazil.
Centromochlus heckelii has the lowest diploid chromosome number (2n = 46) and the only described heteromorphic sex chromosome system in Auchenipteridae. This study presents a population of C. heckelii from the Central Amazon basin with subtle variations in the karyotype composition and a variant W chromosome with distinct morphology and increased C-positive heterochromatin content.
View Article and Find Full Text PDFWorld J Clin Oncol
January 2025
Department of Hematology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China.
Background: Extramedullary plasmacytoma (EMP) represents one of the rarer forms of plasma cell malignancies, capable of impacting a variety of tissues and organs throughout the body. The majority of EMP cases are predominantly found in the head and neck region, especially within the laryngopharynx, as well as in the gastrointestinal tract. While there have been documented instances of oropharyngeal involvement in EMP cases in the academic literature, it is important to note that EMP specifically affecting the uvula is exceedingly uncommon.
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