AI Article Synopsis
- Integra® Bilayer Wound Matrix is a bioengineered tissue made from cross-linked bovine collagen and glycosaminoglycan, designed to support wound healing by allowing for cell migration while reducing inflammation.
- It serves as a scaffold for treating deep soft tissue defects in various types of wounds, providing a stable foundation for repair.
- The text also reviews existing literature on its use and outlines management strategies and treatment algorithms for applying this matrix in complex lower extremity soft tissue reconstruction.
Article Abstract
Integra® Bilayer Wound Matrix is composed of cross-linked bovine tendon collagen and glycosaminoglycan with a semi-permeable polysiloxane membrane. This bioengineered tissue provides a matrix for organized cellular migration and proliferation needed to facilitate wound healing while minimizing an inflammatory response. The scaffold provided by Integra® Bilayer Wound Matrix is particularly helpful for building a durable base for coverage of deep soft tissue defects in wounds of all types. We consider the current literature on Integra® Bilayer Wound Matrix and discuss the peri-application management, as well as introduce our treatment algorithms for its use in complex soft tissue reconstruction in the lower extremity.
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