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Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment. | LitMetric
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Temporary treatment during primary HIV infection does not affect virologic response to subsequent long-term treatment.

Marlous L Grijsen Ferdinand W N M Wit Suzanne Jurriaans Frank P Kroon Emile F Schippers Peter Koopmans Luuk Gras Joep M A Lange Jan M Prins

PLoS One

Academic Medical Center, University of Amsterdam, Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam, Amsterdam, the Netherlands.

Published: January 2015

Temporary cART during primary HIV-infection (PHI) did not select for drug resistance mutations after treatment interruption and did not affect the subsequent virological response to long-term cART. Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from temporary early treatment during PHI.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974663PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089639PLOS

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