StW 573, Little Foot, is the most complete Australopithecus skeleton yet discovered, with many of its bones found in their correct anatomical position. Since the discovery of the in situ skeleton in the Silberberg Grotto in 1997, several teams have attempted to date the fossil. This appeared a simple process because several flowstones are inter-bedded in the breccia above and below StW 573. Dating of these flowstones, using U-Pb (uranium-lead) isotope decay techniques, gave younger results than expected from the fauna and stratigraphic position, around 2.2 Ma (millions of years). Our recent stratigraphic, micromorphological and geochemical studies revealed that the stratigraphy is much more complicated than was previously thought, with localized post-depositional processes leading to the creation of voids within the breccia around the skeleton. These voids were then filled by multiple generations of flowstone growth. The research we present here demonstrates that the proposed dates based on the flowstone deposition can give only a minimum age for StW 573 and that the flowstone formation came after, and probably long after, the breccia deposition. If one takes account of the long evolution of these karst fillings, StW 573 appears to be significantly older than 2.2 Ma.
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http://dx.doi.org/10.1016/j.jhevol.2014.02.014 | DOI Listing |
Eur J Radiol
November 2024
Department of Radiology, LMU University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany; Munich Center for Machine Learning (MCML), Geschwister-Scholl-Platz 1, 80539 Munich, Germany.
This study investigates the predictive capability of radiomics in determining programmed cell death ligand 1 (PD-L1) expression (>=1%) status in non-small cell lung cancer (NSCLC) patients using a newly collected [18F]FDG PET/CT dataset. We aimed to replicate and validate the radiomics-based machine learning (ML) model proposed by Zhao et al. [1] predicting PD-L1 status from PET/CT-imaging.
View Article and Find Full Text PDFEvol Anthropol
December 2024
Evolutionary Studies Institute, University of the Witwatersrand, Johannesburg, South Africa.
A debate has developed with regard to geological ages of hominin fossils attributed to Australopithecus africanus and Australopithecus prometheus in South African Plio-Pleistocene cave deposits. For the Sterkfontein caves (Members 2 and 4), cosmogenic nuclide isochron (Be/Al) dating has yielded age estimates ranging from 3.4 to 3.
View Article and Find Full Text PDFJ Anat
July 2024
Department of Musculoskeletal and Ageing Science, Institute of Life Course & Medical Sciences, Faculty of Health & Life Sciences, the W.H. Duncan Building, University of Liverpool, Liverpool, UK.
There has been a long debate about the possibility of multiple contemporaneous species of Australopithecus in both eastern and southern Africa, potentially exhibiting different forms of bipedal locomotion. Here, we describe the previously unreported morphology of the os coxae in the 3.67 Ma Australopithecus prometheus StW 573 from Sterkfontein Member 2, comparing it with variation in ossa coxae in living humans and apes as well as other Plio-Pleistocene hominins.
View Article and Find Full Text PDFInt J Neurosci
February 2024
Department of Neurology, Chinese PLA General Hospital, Beijing, China.
Objective: We investigated coefficient of variation (CV), gait asymmetry (GA) and phase coordination index (PCI) in cerebral small vessel disease (CSVD) patients during single-task walking (STW) and dual-task walking (DTW) and explored the relationship between above parameters with disease severity and cognitive function.
Methods: This cross-sectional study collected cognitive function indices and gait parameters from 23 healthy controls and 94 patients with CSVD during STW and DTW. According to the Fazekas scales, the severity of CSVD valued by white matter hyperintensity (WMH) were divided into control, mild, moderate, severe and control group.
J Hum Evol
February 2023
Skeletal Biology Research Centre, School of Anthropology and Conservation, University of Kent, Canterbury, UK; Centre for the Exploration of the Deep Human Journey, University of the Witwatersrand, Johannesburg, South Africa.
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