AI Article Synopsis
- The Centre de référence sur les agents tératogènes (CRAT) was established in 1975 as a key organization addressing drug-related risks during pregnancy and has initiated various significant projects in this area.
- The CRAT has developed resources such as a counseling service for healthcare providers, a comprehensive database of over 50,000 pregnancies exposed to drugs, and a user-friendly website for public access.
- Additionally, the organization collaborates with multidisciplinary experts and contributes to European networks to enhance the management and monitoring of drug exposure in pregnancy, fertility, and paternal health.
Article Abstract
Le Centre de référence sur les agents tératogènes (CRAT), founded in 1975, is the first national and international public organization especially involved in the problem of drugs during pregnancy, and during this period of time has been responsible for many initiatives in this field: health care providers information and counsel service, innovating risk assessment methodology, new method for clinical data collection leading to a database including more than 50 000 exposed pregnancies, innovative free access internet website (http://www.lecrat.org), multidisciplinary expert group in French medicines agencies (Afssaps/ANSM) and foundation of a European network "European network teratology information service" (ENTIS). All these innovations represent consequent advances and contribute to a better management of exposed pregnant women and their newborns, as well as the survey and signal detection during pregnancy. The CRAT is also involved in the field of drugs on fertility and on paternal exposures.
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