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Discovery of 2'-hydroxychalcones as autophagy inducer in A549 lung cancer cells. | LitMetric

Discovery of 2'-hydroxychalcones as autophagy inducer in A549 lung cancer cells.

Org Biomol Chem

Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, P.R. China.

Published: May 2014

A series of 2'-hydroxychalcone derivatives was synthesized and the effects of all the compounds on growth of A549 lung cancer cell were investigated. The results showed that all compounds had inhibitory effects on the growth of A549 lung cancer cells and compound possessed the highest growth inhibitory effect and induced autophagy of A549 lung cancer cells.

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Source
http://dx.doi.org/10.1039/c3ob42429dDOI Listing

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