Semmes-Weinstein monofilament (SWM) evaluation for protective sensation in diabetic feet is a widely used tool to guide patient care. Little evidence is available for alternative testing modalities for use when monofilament is not available or is deformed. Multiple varieties of intravenous angiocatheter tubing were subjected to biomechanical testing on a digital scale to assess the force generated once bending was observed by five independently tested raters. A 5.07 SWM (10 g) was tested in similar manner to establish a baseline and validate testing methodology. The 24 gauge × 0.75 in angiocatheter measured the closest to the 5.07 SWM (10 g) at an average force of 22 ± 0.91 g compared with 10.2 ± 0.13 g. Large-gauge angiocatheters measured greater forces. High intra-rater and inter-rater reliability was observed with all values greater than 0.98 (p < 0.001). A 24 gauge × 0.75 in angiocatheter tubing can be used as an alternative to the standard 5.07 SWM (10 g) for testing protective sensation in diabetic feet. Reviewing previously published receiver operating characteristics, this modality would yield estimated sensitivity and specificity values greater than 0.8 and 0.7, respectively, for detecting insensate feet tested at the bilateral metatarsal heads.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.7205/MILMED-D-13-00423 | DOI Listing |
Alzheimers Dement
December 2024
Departments of Neurology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Background: Protective brain barriers, such as blood-brain barrier, become dysfunctional with age. The BBB is a dynamic and selective barrier, gating the passage of molecules and cells to and from the brain. The function of this barrier is critical for the maintenance of brain homeostasis.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Pharmacology and Therapeutics, Florida Chemical Senses Institute, Center for Addiction Research and Education; University of Florida College of Medicine, Gainesville, FL, USA.
Sniffing is a motivated behavior displayed by nearly all terrestrial vertebrates. While sniffing is associated with acquiring and processing odors, sniffing is also intertwined with affective and motivated states. The systems which influence the display of sniffing are unclear.
View Article and Find Full Text PDFJ Indian Soc Periodontol
December 2024
Department of Periodontology, K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
PLoS One
December 2024
Study Center in Emergency Medicine, Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île de-Montréal), Montréal, Québec, Canada.
Introduction: Recent evidence has shown that vitamin C has analgesic and opioid sparing properties in immediate postoperative context. However, this has never been studied for acute musculoskeletal (MSK) emergency department (ED) injuries. The aim of this pilot study is to evaluate the feasibility of conducting a randomized placebo-controlled study to determine the opioid sparing and analgesic effect of vitamin C compared to placebo, in acute MSK injured ED patients.
View Article and Find Full Text PDFSurg Radiol Anat
December 2024
Department of Hand-Foot Microsurgery, Shenzhen Nanshan People's Hospital, No. 89 Taoyuan Road, Nanshan District, Shenzhen, 518052, China.
Objective: This study explored the surgical technique and clinical application of the dorsal metacarpal cutaneous branch flap of the radial digital artery of the index finger.
Methods: Through the anatomical dissection of 10 hand specimens, we examined the origin and characteristics of the artery and its branches towards the hand dorsum. Furthermore, the soft tissue defects of the index finger in 12 patients admitted to our hospital between 2017 and 2021 were surgically repaired using the dorsal metacarpal cutaneous branch flap of the radial digital artery of the index finger.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!