Antibiotics are a mainstay in the treatment of bacterial infections, though their use is a primary risk factor for the development of antibiotic resistance. Antibiotic resistance is a growing problem in pediatric urology as demonstrated by increased uropathogen resistance. Lack of urine testing, nonselective use of prophylaxis, and poor empiric prescribing practices exacerbate this problem. This article reviews antibiotic utilization in pediatric urology with emphasis on modifiable practice patterns to potentially help mitigate the growing rates of antibiotic resistance. This includes urine testing to only treat when indicated and tailor broad-spectrum therapy as able; selective application of antibiotic prophylaxis to patients with high-grade vesicoureteral reflux and hydronephrosis with counseling regarding the importance of compliance; and using local antiobiograms, particularly pediatric-specific antiobiograms, with inpatient versus outpatient data.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943366 | PMC |
| http://dx.doi.org/10.1177/1756287213511508 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of the antibacterial and antibiofilm effect of mycosynthesized silver and selenium nanoparticles and their synergistic effect with antibiotics on nosocomial bacteria.
Microb Cell Fact
January 2025
Microbiology and Immunology Department, Faculty of Medicine, Sohag University, Sohag, Egypt.
Background: The healthcare sector faces a growing threat from the rise of highly resistant microorganisms, particularly Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Pseudomonas aeruginosa (MDR P. aeruginosa). Facing the challenge of antibiotic resistance, nanoparticles have surfaced as promising substitutes for antimicrobial therapy.
View Article and Find Full Text PDFAn unignorable human health risk posed by antibiotic resistome and microbiome in urban rivers: Insights from Beijing, China.
Environ Res
January 2025
College of Water Sciences, Beijing Normal University, Beijing 100875, China. Electronic address:
Urban rivers are the main water bodies humans frequently come into contact with, so the risks posed are closely monitored. Antibiotic resistance genes (ARGs) residues in reclaimed water pose serious risks to human health. There are urgent needs to improve the understanding of distribution of and risks posed by ARGs in urban rivers.
View Article and Find Full Text PDFThe symbiont Wolbachia increases resistance to bifenthrin in Ectropis grisescens by regulating the host detoxification function.
Ecotoxicol Environ Saf
January 2025
State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, China. Electronic address:
The global issue of insecticide resistance among pests is a major concern. Ectropis grisescens Warren (Lepidoptera: Geometridae), is a highly destructive leaf-eating pest distributed in tea plantations throughout China and Japan, and has exhibited resistance to various insecticides. Recent studies suggest that insect symbionts play a role in influencing insecticide resistance, however, their specific involvement in E.
View Article and Find Full Text PDFMicroalgal-based urea wastewater treatment with p-Hydroxybenzoic acid enhances resource recovery and mitigates biological risks from Bisphenol A.
Water Res
January 2025
Key Laboratory of Groundwater Resources and Environment (Jilin University), Ministry of Education, Jilin University, Changchun 130021, Jilin, PR China; Chongqing Research Institute, Jilin University, 401120 Chongqing, PR China; Jilin Provincial Key Laboratory of Water Resources and Environment, Jilin University, Changchun 130021, Jilin, PR China. Electronic address:
Efficient nutrient recovery from source-separated urine is vital for wastewater treatment, with microalgae as a promising solution. However, bisphenol A (BPA) in urine can hinder microalgal resource recovery and pose water quality risks. The role of plant hormones in enhancing microalgal growth and pollutant removal is known, but their impact on BPA-laden urine treatment is not well-studied.
View Article and Find Full Text PDFYafN-YafO toxin-antitoxin system contributes to stress resistance and virulence of avian pathogenic Escherichia coli.
Poult Sci
January 2025
Institute of Agricultural Science and Technology Development, College of Veterinary Medicine, Yangzhou University, Yangzhou, PR China; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, PR China; Key Laboratory of Avian Bioproduct Development, Ministry of Agriculture and Rural Affairs, Yangzhou, PR China; Institutes of Agricultural Science and Technology Development, Yangzhou University, Yangzhou, PR China. Electronic address:
Avian pathogenic Escherichia coli (APEC) is a major threat to the poultry industry, causing bloodstream and extraintestinal infections. Type II toxin-antitoxin (TA) systems are known to aid bacterial pathogens in adapting to stress, promoting persister cell formation, and enhancing virulence. While type II TA systems have been extensively studied in many pathogens, APEC-derived TAs have received limited attention.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!