A cavitand with ionic, but nonionizable "feet" folds around hydrophobic guests in D2O. Short alkanes and ibuprofen are included and exchange rates are slow on the NMR timescale. Normal octanoyl groups show good affinity for the cavitand and the gastric peptide ghrelin is bound at low pH and physiological temperature.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c4cc01643b | DOI Listing |
Publication Analysis
Top Keywords
complexation alkyl
4
alkyl groups
4
groups ghrelin
4
ghrelin deep
4
deep water-soluble
4
water-soluble cavitand
4
cavitand cavitand
4
cavitand ionic
4
ionic nonionizable
4
nonionizable "feet"
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!