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A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus.
PLoS Negl Trop Dis
December 2024
Life Science Research Centre, Faculty of Science, University of Ostrava, Ostrava, Czechia.
Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures of visceral organs. The disease is exacerbated if a parasite harbors Leishmania RNA viruses (LRVs) of the family Pseudototiviridae.
View Article and Find Full Text PDFExploring the significant genetic diversity of Iranian isolates of Leishmania RNA virus 2 using whole genome sequence analysis.
BMC Infect Dis
December 2024
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Background: Our work presents the whole genome sequence and phylogenetic analysis of five Leishmania RNA virus 2 (LRV2) isolates obtained from patients with cutaneous leishmaniasis (CL) in Iran.
Methods: The whole genome sequencing of LRV2 was performed using a primer walking approach. The resulting sequences were analyzed for genetic and haplotype diversity, highlighting their independent evolution and significant genetic divergence.
Efficacy and Tolerability of Olaparib Plus Paclitaxel in Patients with Gastric Cancer Associated with Hereditary Breast and Ovarian Cancer.
Curr Oncol
October 2024
Cancer Medicine, National Hospital Organization Kyoto Medical Center, Fushimi-ku, Kyoto 612-8555, Kyoto, Japan.
, a gram-negative, flagellated, helical bacterium, is a common cause of chronic gastric infection worldwide. According to the World Health Organization, infection, a specific carcinogenic factor, was the leading cause of gastric cancer (GC) in 2014 worldwide (80%). infection causes GC in >98% of patients in East Asian countries, including Japan.
View Article and Find Full Text PDFThe burden and trend of intestinal parasitosis among women at Berekum, Ghana: a 9-year retrospective study.
BMC Infect Dis
November 2024
Department of Biomedical Sciences, School of Basic and Biomedical Sciences, University of Health and Allied Sciences, Ho, Ghana.
Article Synopsis
- Intestinal parasitic infections (IPIs) are significant public health concerns, particularly in low and middle-income countries, where they can severely affect vulnerable populations through contaminated food and water.
- A study analyzing 9 years of stool examination data found an overall prevalence of 21.20% of IPIs, with the highest rates among patients aged 70-79 and in the year 2020.
- The most common parasites identified were intestinal flagellates, which accounted for 98.31% of the infections diagnosed in the study.
The association of serum level and polymorphisms of IFN-γ (rs2069705) with the susceptibility to cutaneous leishmaniasis.
Cytokine
December 2024
College of Medicine, University of Diyala, Diyala governorate, Iraq.
Leishmaniasis, a broad range of parasitic diseases, caused by Leishmania which is a flagellated intracellular protozoan parasite of the family Trypanosomatidae. The severity of leishmaniasis diseases ranges from minor cutaneous lesions to severe visceral illnesses that can be disfiguring and life-threatening. Cytokines are glycoprotein molecules produced by various cells in response to various immunological triggers.
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