AI Article Synopsis
- The study examined outbreaks of respiratory disease in pigs to identify the presence of swine influenza virus (SIV), isolating and sequencing strains from 14 cases.
- Researchers found that the responsible virus strains belonged to H1N1, H3N2, and H1N2 subtypes, with 11 cases showing signs of genetic reassortment.
- A longitudinal study of H1N1 SIV in closed groups of pigs revealed co-circulation of different virus variants and the emergence of reassortants, stressing the need for improved understanding of SIV epidemiology in endemic farms.
Article Abstract
In the present study, outbreaks of respiratory disease were investigated for the presence of swine influenza virus (SIV). In 14 cases the circulating SIV strains were isolated, fully sequenced and compared with other known SIVs. The viruses causing the outbreaks belonged to the H1N1 (including human pandemic H1N1), H3N2 and H1N2 subtypes. In 11/14 cases the phylogenetic analyses indicated the occurrence of probable reassortment events. In the second part of the study, the genetic evolution of H1N1 SIV was assessed in a longitudinal study in closed groups of pigs over six months. Sequencing of the 22 isolates indicated co-circulation of two different variants for the same virus, as well as the emergence of SIV reassortants at certain time-points. These results indicate that reassortment events in SIV are common, and point towards the need for a better understanding of the epidemiology of SIV, particularly in endemic farms.
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| http://dx.doi.org/10.1016/j.vetmic.2014.02.031 | DOI Listing |
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