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Advancement of the Dragon Heart 7-Series for Pediatric Patients With Heart Failure.
Artif Organs
January 2025
BioCirc Research Laboratory, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.
Background: Safe and effective pediatric blood pumps continue to lag far behind those developed for adults. To address this growing unmet clinical need, we are developing a hybrid, continuous-flow, magnetically levitated, pediatric total artificial heart (TAH). Our hybrid TAH design, the Dragon Heart (DH), integrates both an axial flow and centrifugal flow blood pump within a single, compact housing.
View Article and Find Full Text PDFLactoferrin targeting INTL1 receptor inhibits hepatocellular carcinoma progression via apoptosis and cell cycle signaling pathways.
Sci Rep
December 2024
Department of Life Sciences, College of Life Sciences, National Chung Hsing University, Kuo Kuang Rd., Taichung, 402, Taiwan.
Hepatocellular carcinoma (HCC) constitutes 90% of liver cancer cases and ranks as the third leading cause of cancer-related mortality, necessitating urgent development of alternative therapies. Lactoferrin (LF), a natural iron-binding glycoprotein with reported anticancer effects, is investigated for its potential in liver cancer treatment, an area with limited existing studies. This study focuses on evaluating LF's anti-liver cancer effects on HCC cells and assessing the preventive efficacy of oral LF administration in a murine model.
View Article and Find Full Text PDFEnhancing external quantum efficiency in a sky-blue OLED by charge transfer via Si quantum dots.
Discov Nano
December 2024
International Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, 305-0044, Japan.
Article Synopsis
- Organic light-emitting diodes (OLEDs) seek to achieve near 100% quantum efficiency (QE) by utilizing excitons, but creating effective organic materials can be slow.
- A new approach involves adding inorganic quantum dots, which serve as charge generation centers, to the organic luminescent layer, allowing unlimited exciton formation.
- Using Silicon quantum dots (SiQDs), researchers showed significant improvements in external QE and electron transfer times, paving the way for wider applications across different colors and materials.
PtosisDiffusion: a training-free workflow for precisely predicting post-operative appearance in blepharoptosis patients based on diffusion models.
Front Cell Dev Biol
October 2024
Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, Zhejiang, China.
Purpose: This study aims to develop a diffusion-based workflow to precisely predict postoperative appearance in blepharoptosis patients.
Methods: We developed PtosisDiffusion, a training-free workflow that combines face mesh with ControlNet for accurate post-operative predictions, and evaluated it using 39 preoperative photos from blepharoptosis patients. The performance of PtosisDiffusion was compared against three other diffusion-based methods: Conditional Diffusion, Repaint, and Dragon Diffusion.
Psychological barriers in children: an exploratory study on Dengue transmission using an adapted DIPB scale.
Front Psychol
October 2024
School of Education, University of Brasília, Brasília, Brazil.
Dengue is an arboviral infection found in tropical and subtropical regions transmitted by hematophagous mosquitoes from the genus spp. and responsible for millions of cases every year. Public campaigns and educational curriculum are designed to educate people, including children.
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