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Do social relationships at work enhance creativity and innovative behavior? Role of psychological safety.
Acta Psychol (Amst)
January 2025
OB HRM Area, Management Development Institute, Gurgaon, Haryana, India. Electronic address:
The study uses social exchange theory to examine how social relationships affect individual involvement in creativity at work and innovative behavior, mediated by psychological safety. The study disentangles the social relationships at work as informal and formal relationships in terms of two plausible theoretical variables, workplace friendliness and perceived affective climate respectively, for the above purpose. Over a period of three-months, data collection was conducted in the IT and ITeS industry, with a sample of 515 participants and 105 team leads, using a two-pronged approach involving data from both team leads and their subordinates.
View Article and Find Full Text PDFThe Role of Atmospheric Composition in Defining the Habitable Zone Limits and Supporting Growth.
Life (Basel)
January 2025
Centre sur la Vie dans l'Univers, Université de Genève, 1211 Geneva, Switzerland.
Studying exoplanet atmospheres is essential for assessing their potential to host liquid water and their capacity to support life (their habitability). Each atmosphere uniquely influences the likelihood of surface liquid water, defining the habitable zone (HZ)-the region around a star where liquid water can exist. However, being within the HZ does not guarantee habitability, as life requires more than just liquid water.
View Article and Find Full Text PDFDisrupting the dangerous alliance: Dual anti-inflammatory and anticoagulant strategy targets platelet-neutrophil crosstalk in sepsis.
J Control Release
January 2025
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.. Electronic address:
Sepsis is a life-threatening disease characterized by excessive systemic inflammation and coagulopathy. Platelets and neutrophils form a "dangerous alliance" through crosstalk, promoting the inflammatory cytokine storm and coagulation disorders during sepsis. Platelet-neutrophil crosstalk leads to the formation of platelet-neutrophil complexes (PNCs), which are the central "protagonists" of this "dangerous alliance.
View Article and Find Full Text PDFExosome-loading miR-205: a two-pronged approach to ocular neovascularization therapy.
J Nanobiotechnology
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Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200080, China.
Pathological neovascularization is a hallmark of many vision-threatening diseases. However, some patients exhibit poor responses to current anti-VEGF therapies due to resistance and limited efficacy. Recent studies have highlighted the roles of noncoding RNAs in various biological processes, paving the way for RNA-based therapeutics.
View Article and Find Full Text PDFNucleic acid joining enzymes: biological functions and synthetic applications beyond DNA.
Biochem J
January 2025
School of Science, University of Waikato, Hamilton, Waikato, 3216, New Zealand.
DNA-joining by ligase and polymerase enzymes has provided the foundational tools for generating recombinant DNA and enabled the assembly of gene and genome-sized synthetic products. Xenobiotic nucleic acid (XNA) analogues of DNA and RNA with alternatives to the canonical bases, so-called 'unnatural' nucleobase pairs (UBP-XNAs), represent the next frontier of nucleic acid technologies, with applications as novel therapeutics and in engineering semi-synthetic biological organisms. To realise the full potential of UBP-XNAs, researchers require a suite of compatible enzymes for processing nucleic acids on a par with those already available for manipulating canonical DNA.
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