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Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study.
Environ Pollut
January 2025
Department of Environmental Health Sciences, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA; Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. Electronic address:
Background: Previous epidemiological studies on the associations between hazardous air pollutants (HAPs) and breast cancer (BC) have largely neglected rural, medically underserved areas in the United States, which differ in exposures and disparities compared to urban areas.
Objectives: We aimed to examine the associations between carcinogenic HAPs and BC risk in a rural population.
Methods: Using a nested case-control design, 574 cases and 2295 incidence density-sampled controls matched 1:4 on index age and race were included from the Arkansas Rural Community Health study.
Allergens Responsible for Contact Allergy in Children From 2010 to 2024: A Systematic Review and Meta-Analysis.
Contact Dermatitis
January 2025
Department of Dermatology and Allergy, Herlev and Gentofte-Copenhagen University Hospital, Copenhagen, Denmark.
Contact allergy (CA) is a frequent condition in children; however, newer estimates of the prevalence of CA in children are lacking. Herein, we aim to provide an estimate of the prevalence of CA in children from 2010 to 2024. Two authors independently searched PubMed, Embase and Web of Science for studies reporting the prevalence of positive patch tests (PPTs) to allergens in populations including ≥ 100 children (< 18 years).
View Article and Find Full Text PDFFabrication of Quasi-Solid Polymer Electrolytes for Lithium Metal Battery via Photopolymerization-Induced Microphase Separation.
ACS Appl Mater Interfaces
January 2025
Universite de Pau et des Pays de l'Adour, E2S UPPA, CNRS, IPREM, 64053, Pau, France.
The photopolymerization-induced microphase separation (photo-PIMS) process involving a reactive polymer block was implemented to fabricate nanostructured quasi-solid polymer electrolytes (QSPEs) for use in lithium metal batteries (LMBs). This innovative one-pot fabrication enhances interfacial properties in LMBs by enabling nanostructuring of QSPE directly onto the electrodes. This process also allows for customization of QSPE structural dimensions by tweaking the architecture and molar mass of poly[(oligo ethylene glycol) methyl ether methacrylate--styrene] (P(OEGMA--S)) macromolecular chain transfer agent.
View Article and Find Full Text PDFOxidative stress reactions in rats with pulmonary injuries induced by sulfur mustard (1 LD).
Hum Exp Toxicol
December 2024
Department of Respiration, The 80th Group Army Hospital of People's Liberation Army, Weifang, China.
Objective: Sulfur mustard (SM) is an important chemical warfare agent. The mechanisms underlying SM toxicity have not been completely elucidated. However, oxidative stress and the subsequent damage to macromolecules have been considered ascrucial steps in SM toxicity.
View Article and Find Full Text PDFPPS-TLR7/8 agonist nanoparticles equip robust anticancer immunity by selectively prolonged activation of dendritic cells.
Biomaterials
May 2025
Wuya college of innovation, Shenyang Pharmaceutical University, No.103, Wenhua Road, Shenyang, 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, China. Electronic address:
Checkpoint inhibitor therapies do not benefit all patients, and adjuvants play a critical role in boosting immune responses for effective cancer immunotherapy. However, their systemic toxicity and suboptimal activation kinetics pose significant challenges. Here, this study presented a linker-based strategy to modulate the activation kinetics of Toll-like receptor 7/8 (TLR7/8) agonists delivered via poly (propylene sulfide) nanoparticles (PPS NPs).
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