AI Article Synopsis
- The study aimed to determine whether adults with metabolic syndrome (MetSyn) have stronger sympathetic and blood pressure responses to exercise compared to healthy individuals.
- Twelve adults with MetSyn and twelve healthy adults underwent handgrip exercises while measuring heart rate, blood pressure, and muscle sympathetic nerve activity.
- Results showed no significant differences in sympathetic or blood pressure responses between MetSyn patients and healthy controls during exercise, suggesting that MetSyn does not lead to exaggerated responses in younger adults.
Article Abstract
Aim: Based on reports of exaggerated blood pressure responses to whole-body exercise in patients with metabolic syndrome (MetSyn), we tested the hypothesis that MetSyn adults would exhibit augmented sympathetic and pressor responses to mechanoreflex and metaboreflex activation when compared with healthy, age-matched control subjects.
Methods: We studied 12 adults with MetSyn (34±3years) and 12 healthy control subjects (34±3years). Heart rate (HR; ECG), blood pressure (BP; finger photoplethysmography), and MSNA (microneurography of the peroneal nerve) were measured during: (1) static handgrip exercise at 15% of maximal voluntary contraction (MVC), and (2) static handgrip exercise at 30% MVC to fatigue, followed by post-exercise ischemia (PEI). Increases in MSNA, HR, and BP were assessed.
Results: During static exercise at both 15 and 30% MVC, increases in MSNA, HR, and BP were not different between groups. MSNA remained significantly elevated from baseline during PEI and responses were not different between groups.
Conclusion: Sympathetic and pressor responses to mechanoreflex and metaboreflex activation are not augmented in younger adults with MetSyn.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058385 | PMC |
| http://dx.doi.org/10.1016/j.autneu.2014.03.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!