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Sarcoid-like Reaction in a Patient With Colon Cancer: A Case Report and Mini-Review.
Int J Surg Pathol
November 2024
Department of Surgical Pathology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Sarcoidosis is a multisystemic and chronic inflammatory disorder characterized by the manifestation of epithelioid cell granulomas in various organs. Sarcoid-like reactions occur in patients who do not fulfill the diagnostic criteria for sarcoidosis but present with similar clinical and histological features. An 80-year-old man presented to our hospital with several subcutaneous nodules on the extremities.
View Article and Find Full Text PDFThe Great Mimicker Unmasked: A Case Report of Cardiac Sarcoidosis Hidden by Myocardial Infarction and Colon Cancer.
J Cardiovasc Echogr
September 2024
Department of Surgical, Medical and Molecular Pathology and Critical Area, Radiology Division, University of Pisa, Pisa, Italy.
Article Synopsis
- Cardiac sarcoidosis is a complex condition that can mimic other diseases, making diagnosis difficult and requiring careful evaluation and imaging techniques.
- A case study highlights a patient with cardiac sarcoidosis who also had coronary artery disease and colon cancer, illustrating the need to consider multiple potential diagnoses.
- Late gadolinium enhancement is important for assessing arrhythmic risk and guiding treatment, emphasizing that clinical scenarios shouldn't be oversimplified by focusing solely on one condition.
: A HERV Turn-On for Autoimmunity, Neurodegeneration, and Cancer?
Microorganisms
September 2024
Department of Biomedical Science, University of Sassari, 07100 Sassari, Italy.
Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that, over millions of years, became integrated into the human genome. While normally inactive, environmental stimuli such as infections have contributed to the transcriptional reactivation of HERV-promoting pathological conditions, including the development of autoimmunity, neurodegenerative disease and cancer. What infections trigger HERV activation? subspecies (MAP) is a pluripotent driver of human disease.
View Article and Find Full Text PDFGastrointestinal Manifestations of Sarcoidosis: A State-of-the-Art, Comprehensive Review of the Literature-Practical Clinical Insights and Many Unmet Needs on Diagnosis and Treatment.
Pharmaceuticals (Basel)
August 2024
Pulmonology Unit, Department of Medical Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Article Synopsis
- This literature review examines the role of the gastrointestinal (GI) tract in sarcoidosis, which is a rare inflammatory disease that can be difficult to diagnose and treat due to overlapping symptoms with other GI disorders.* -
- GI sarcoidosis can impact any area of the gastrointestinal system, particularly the stomach and small intestine, leading to symptoms that range from mild discomfort to serious complications like obstruction or perforation.* -
- Current treatment options primarily involve corticosteroids, but their long-term effectiveness and safety are questionable, highlighting the urgent need for better diagnostic methods and standardized treatment protocols.*
Experience with Laparoscopic and Robotic Colon Surgery Together with Other Major Minimally Invasive Procedures for Unrelated Pathologies.
J Laparoendosc Adv Surg Tech A
July 2024
Meritus Surgical Specialists, Meritus Health, Hagerstown, Maryland, USA.
Indications for combined colon surgery together with other procedures include oncologic multivisceral resections and abdominal trauma. It is unclear if combining minimally invasive (MI) colon surgery with unrelated other procedures increases the risk for complications. The surgical database from two institutions during a 10-year period was queried for combined colon surgeries together with other interventions.
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