AI Article Synopsis
Article Abstract
The aim of our study was to establish the genetic differentiation of the population of the province of Wielkopolska (Greater Poland) for 17 Y-STRs and 8 Y-SNPs and comparison of the Polish population with other selected populations. The investigations included 201 unrelated male inhabitants of the Greater Poland region We found 184 unique haplotypes for 17 Y-STR. The haplotype discrimination capacity was 0.96. The most frequent haplotype Ht-50 was found in 3 samples and 7 haplotypes observed twice. Further, the same samples were analyzed with Y-8 SNPs markers. We obtained 40 haplotypes. The haplotype discrimination capacity was 0.20. The most frequent haplotype was presented in 38 samples. A total of 4 different haplogroups were established. Haplogroup K= 19%, IJ = 7%, R1a1 = 59% and R1b = 15%. The HD value of Y-SNPs/Y-STRs was 0.9883.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Y-Chromosomal insights into the paternal genealogy of the Kerey tribe have called into question their descent from the Stepfather of Genghis Khan.
PLoS One
September 2024
International Science Complex "Astana", Astana, Kazakhstan.
The Kerey is one of the prominent Kazakh tribes and has long been a subject of ethnographic scrutiny, with a lack of consensus on its origin and traditional genealogy. Their historical significance, intertwined with the emergence of the empire established by Genghis Khan, necessitates a comprehensive understanding of their genetic history. This study focuses on unraveling the genetic heritage of the Kerey tribe.
View Article and Find Full Text PDFY-chromosome analysis recapitulates key events of Mediterranean populations.
Heliyon
August 2024
BIOMICs Research Group, Department of Z. and Cell Biology A., Faculty of Pharmacy, Lascaray Research Center, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
The remarkable geographical situation of the Mediterranean region, located between Europe, Africa, and Asia, with numerous migratory routes, has made this area a crucible of cultures. Studying the Y-chromosome variability is a very performant tool to explore the genetic ancestry and evaluate scenarios that may explain the current Mediterranean gene pool. Here, six Mediterranean populations, including three Balearic Islands (Ibiza, Majorca, and Minorca) and three Southern Italian regions (Catanzaro, Cosenza, and Reggio di Calabria) were typed using 23 Y-STR loci and up to 39 Y-SNPs and compared to geographically targeted key reference populations to explore their genetic relationship and provide an overview of Y-chromosome variation across the Mediterranean basin.
View Article and Find Full Text PDFMale-specific age prediction based on Y-chromosome DNA methylation with blood using pyrosequencing.
Forensic Sci Int Genet
July 2024
School of Forensic Medicine, Shanxi Medical University, Taiyuan, Shanxi 030009, PR China. Electronic address:
Age prediction is an important aspect of forensic science that offers valuable insight into identification. In recent years, extensive studies have been conducted on age prediction based on DNA methylation, and numerous studies have demonstrated that DNA methylation is a reliable biomarker for age prediction. However, almost all studies on age prediction based on DNA methylation have focused on age-related CpG sites in autosomes, which are concentrated on single-source DNA samples.
View Article and Find Full Text PDFA DNA typing panel of 201 genetic markers for degraded samples: development and validation.
Yi Chuan
April 2024
Bioinformatics Center of Academy of Military Medical Sciences, Beijing 100850, China.
With the increasing number of complex forensic cases in recent years, it's more important to combine the different types of genetic markers such as short tandem repeats (STRs), single nucleotide polymorphisms (SNPs), insertion/deletion polymorphisms (InDels), and microhaplotypes (MHs) to provide more genetic information. In this study, we selected totally 201 genetic markers, including 24 autosomes STRs (A-STRs), 24 Y chromosome STRs (Y-STRs), 110 A-SNPs, 24 Y-SNPs, 9 A-InDels, 1 Y-InDel, 8 MHs, and Amelogenin to establish the HID_AM Panel v1.0, a Next-Generation Sequencing (NGS) detection system.
View Article and Find Full Text PDFDevelopment and validation of YARN: A novel SE-400 MPS kit for East Asian paternal lineage analysis.
Forensic Sci Int Genet
July 2024
MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China; Institute of Archaeological Science, Fudan University, Shanghai 200433, China; MOE Laboratory for National Development and Intelligent Governance, Fudan University, Shanghai 200433, China. Electronic address:
Y-chromosomal short tandem repeat polymorphisms (Y-STRs) and Y-chromosomal single nucleotide polymorphisms (Y-SNPs) are valuable genetic markers used in paternal lineage identification and population genetics. Currently, there is a lack of an effective panel that integrates Y-STRs and Y-SNPs for studying paternal lineages, particularly in East Asian populations. Hence, we developed a novel Y-chromosomal targeted panel called YARN (Y-chromosome Ancestry and Region Network) based on multiplex PCR and a single-end 400 massive parallel sequencing (MPS) strategy, consisting of 44 patrilineage Y-STRs and 260 evolutionary Y-SNPs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!