Unlabelled: The aim of the study was to compare the efficacy of pulmonary vein antrum isolation (PVAI), extended PVAI and ganglionic plexi (GP) ablation in persistent AF.
Methods: One hundred and twenty patients 56.2 ± 8.8 years old were randomized into three groups: GP ablation (n = 37), PVAI (n = 42), and extended PVAI (n = 41). The following parameters were studied: sinus rhythm restoration, vagal reactions, fluoroscopy time, procedure duration, lesion surface area. In 16 months after the procedure, echocardiography and Holter monitoring were performed.
Results: Significant differences were found in the amount of X-ray exposure, procedure duration, lesion surface area and vagal reactions. In all the cases, atrial mechanical function worsened after the procedure. However, there were no significant differences between the groups. Sixteen months after the procedure, sinus rhythm without antiarrhythmic therapy was maintained in 38% of patients in GP group, in 56% of patients in PVAI group and in 69% of patients in extended PVAI group.
Conclusions: In persistent AF, the extended PVAI is more effective than PVAI and GP ablation. After the PVAI or extended PVAI, abnormalities of the left atrial mechanical function occurred if the lesion area exceeded 25% of the total LA surface area.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955813 | PMC |
| http://dx.doi.org/10.1556/IMAS.6.2014.1.5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Targeting non-pulmonary vein triggers in persistent atrial fibrillation: results from a prospective, multicentre, observational registry.
Europace
December 2021
Texas Cardiac Arrhythmia Institute, St. David's Medical Center, 3000 N. IH-35, Suite 720, Austin, TX 78705, USA.
Aims: We evaluated the efficacy of an ablation strategy empirically targeting pulmonary veins (PVs) and posterior wall (PW) and the prevalence and clinical impact of extrapulmonary trigger inducibility and ablation in a large cohort of patients with persistent atrial fibrillation (PerAF).
Methods And Results: A total of 1803 PerAF patients were prospectively enrolled. All patients underwent pulmonary vein antrum isolation (PVAI) extended to the entire PW.
Long-term outcomes of catheter ablation in patients with longstanding persistent atrial fibrillation lasting less than 2 years.
J Cardiovasc Electrophysiol
December 2018
Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, Texas.
Introduction: Outcome data after catheter ablation (CA) for longstanding persistent atrial fibrillation (LSPAF) lasting less than 2 years are limited and highly variable with different ablation approaches. We aimed to assess the long-term outcomes in patients with LSPAF lasting less than 2 years undergoing extended pulmonary vein antrum isolation (PVAI) versus those with additional non-pulmonary vein (PV) trigger ablation.
Methods And Results: In this prospective analysis, 381 consecutive patients with LSPAF lasting less than 2 years (age: 64 ± 9 years, 76% male, atrial fibrillation duration: 19 ± 5 months) undergoing their first CA were classified into two groups: Group 1 (n = 104) received PVAI extended to PW plus isolation of superior vena cava (SVC) and Group 2 ( n = 277) received PVAI + PW + SVC + non-PV-trigger ablation.
Proven isolation of the pulmonary vein antrum with or without left atrial posterior wall isolation in patients with persistent atrial fibrillation.
Heart Rhythm
January 2016
Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin, Texas; Department of Biomedical Engineering, University of Texas, Austin, Texas; California Pacific Medical Center, San Francisco, California; Dell Medical School, Austin, Texas. Electronic address:
Background: It is unclear whether isolation of the left atrial posterior wall (LAPW) offers additional benefits over pulmonary vein antrum isolation (PVAI) alone in patients with persistent atrial fibrillation (AF).
Objective: We sought to determine the impact of PVAI and LAPW isolation (PVAI+LAPW) versus PVAI alone on the outcome of ablation of persistent AF.
Methods: During the first procedure, PVAI was performed in 20 patients (group 1), whereas in 32 patients (group 2), PVAI was extended to the left atrial (LA) septum and coronary sinus (CS), and isolation of the LAPW was targeted (ePVAI+LAPW).
Catheter ablation of atrial fibrillation in patients with mechanical mitral valve: long-term outcome of single procedure of pulmonary vein antrum isolation with or without nonpulmonary vein trigger ablation.
J Cardiovasc Electrophysiol
August 2014
Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin, Texas, USA.
Introduction: It is unclear whether extended pulmonary vein antrum isolation (PVAI) plus nonpulmonary vein (non-PV) trigger elimination prevents more arrhythmia recurrence than PVAI alone in patients with mechanical mitral valve (MMV) undergoing AF ablation. This study compared the efficacy and long-term outcome of 2 ablation strategies--PVAI alone versus extended PVAI plus non-PV trigger elimination--for the treatment of AF in patients with MMV.
Methods And Results: One hundred and nine consecutive AF patients with MMV were divided into 2 groups: standard PVAI was performed in group 1 (N = 45); in group 2 (N = 64) PVAI was extended to the LA posterior wall, LA septum, and CS; and all non-PV triggers were eliminated.
Unlabelled: The aim of the study was to compare the efficacy of pulmonary vein antrum isolation (PVAI), extended PVAI and ganglionic plexi (GP) ablation in persistent AF.
Methods: One hundred and twenty patients 56.2 ± 8.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!