Objective: To investigate the diagnostic value of contrast-enhanced ultrasonography (CEUS) in preoperative Borrmann classification of gastric cancer.
Methods: Asulfur hexafluonde-filled microbubble ultrasound contrast agent and continuous real-time imaging technique of contrast pulse sequencing were used. Two hundred and eighty-five patients with gastric cancer confirmed by biopsies who received preoperative CEUS examination were involved in this study. CEUS results were compared with postoperative pathological findings.
Results: The accuracy rate of CEUS in determining the Borrmann classification of gastric cancer was 92.3%(263/285). The accuracy rates of BorrmannI(, II(, III(, IIII(, and IIIII( were 100%(12/12), 90.6%(77/85), 92.6%(126/136), 95.7%(45/47), and 60.0%(3/5) respectively.
Conclusion: CEUS is a useful diagnostic method for preoperative Borrmann classification of gastric cancer.
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Abdom Radiol (NY)
January 2025
Department of Medical Imaging, Tongji Hospital, Tongji University, No. 389, Xincun Road, Putuo District, Shanghai, 200065, China.
Objectives: This study aimed to compare apparent diffusion coefficient (ADC) values derived from diffusion-weighted imaging (DWI) of different Borrmann types of advanced gastric cancer (AGC) and correlate these ADC values with Ki-67 expression and serum CEA levels in AGC.
Methods: A total of 84 patients with AGC who underwent DWI of the upper abdomen before tumor resection in our hospital between June 2014 and July 2018 were included in the present study. DWI was obtained with a single-shot echo planar imaging sequence in the axial plane (b values: 0, 100, 700 and 1000 s/mm).
Front Oncol
December 2024
Department of Gastrointestinal, Hengshui People's Hospital, Hengshui, Hebei, China.
Objective: To develop and validate a model for preoperative prediction of positive proximal margins for adenocarcinoma of the esophagogastric junction (AEG) by transabdominal approach, and to analyze the safe margin distances for patients with different risks of positive proximal margins.
Materials And Methods: A retrospective analysis was performed on 284 AEG patients who underwent surgery via the transabdominal approach at Hengshui People's Hospital between January 2017 and December 2023. Patients were divided into a training set (=201, first five years) and a test set (=83, last two years).
BMC Gastroenterol
September 2024
Department of Gastroenterology Surgery, The Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian Shahekou District Southwest Road No. 826, Dalian, 116033, PR China.
Background: The stromal cell derived factor 2 (SDF2) relates closely to the occurrence and development of several kind of cancers. There are few studies to investigate the clinicopathological and prognostic significance of SDF2 in gastric cancer (GC) patients.
Methods: We detected SDF2 expression in GC and normal gastric tissues using bioinformatics, western blot and immunohistochemistry.
World J Gastrointest Surg
August 2024
Department of Oncology, Zhejiang Hospital, Hangzhou 310013, Zhejiang Province, China.
Background: This study investigated the construction and clinical validation of a predictive model for neuroaggression in patients with gastric cancer. Gastric cancer is one of the most common malignant tumors in the world, and neuroinvasion is the key factor affecting the prognosis of patients. However, there is a lack of systematic analysis on the construction and clinical application of its prediction model.
View Article and Find Full Text PDFAcad Radiol
January 2025
Department of Pathology, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, China. Electronic address:
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