In this study, we describe the synthesis of 1,4-disustituted-1,2,3-triazolo-quinazoline ribonucleosides or acyclonucleosides by means of 1,3-dipolar cycloaddition between various O or N-alkylated propargyl-quinazoline and 1'-azido-2',3',5'-tri-O-benzoylribose or activated alkylating agents under microwave conditions. None of the compounds selected showed significant anti-HCV activity in vitro.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271638 | PMC |
| http://dx.doi.org/10.3390/molecules19033638 | DOI Listing |
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