Lanthanum(III) triflate catalyzed direct amidation of esters.

Org Lett

Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.

Published: April 2014

Lanthanum trifluoromethanesulfonate is an effective single-component catalyst for synthesizing a variety of amides directly from esters and amines under mild conditions. Highly selective amidation of esters and amines, as well as catalyst-controlled amidation of esters, demonstrated the effectiveness of the catalyst system.

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Source
http://dx.doi.org/10.1021/ol500593vDOI Listing

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