AI Article Synopsis
- A new diterpenoid (1) and a new sesquilignan (2) were discovered from the plant Aglaia odorata var. microphyllina, alongside three previously known compounds (3, 4, 5).
- The structural analysis of these compounds was performed using advanced NMR spectroscopy techniques.
- Compound 1 showed promising cytotoxic activity against the K562 cell line, with an IC50 value of 12.5 microg/mL, indicating potential for further research in cancer treatment.
Article Abstract
One new diterpenoid, 11alpha,12betaH-dolabella-4,8(17)-dien-3alpha,7beta,18-triol (1) and one new sesquilignan, 9-methoxy-7',8'-cis-7",8"-cis-buddlenol B (2), together with three known compounds, (+)-diasyringaresinol (3), N-methyl-5- hydroxy-delta3-pyrrolin-2-one (4) and marmin (5), have been isolated from Aglaia odorata var. microphyllina. Their structures were determined using 1D and 2D NMR spectroscopy. Compound 1 exhibited cytotoxic activity against the K562 cell line with an IC50 value of 12.5 microg/mL.
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