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Performance of the Edwards Sapien 3 bioprosthesis in atrioventricular valve position: a case series.
Eur Heart J Case Rep
December 2024
Paediatric Interventional Cardiology Unit, Vall d'Hebron Hospital, Paseo de la Vall d'Hebron, 119-129, 08035 Barcelona, Spain.
Background: The Edwards Sapien percutaneous valve (Edwards Lifesciences, Irvine, CA, USA) is a promising therapeutic option for congenital atrioventricular disease mostly because of the possibility to accommodate somatic growth with balloon dilatation.
Case Summary: This article reports the performance of the Edwards Sapien 3 valve in atrioventricular valve position in four paediatric patients.
Discussion: Despite aggressive antiplatelet and anticoagulation strategies, most patients showed early bioprosthesis dysfunction, with increasing gradient not related with somatic growth.
7-Year outcomes after surgical aortic valve replacement with a stented bovine pericardial bioprosthesis in over 1100 patients: a prospective multicenter analysis.
Eur J Cardiothorac Surg
November 2024
Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands.
Objectives: Safety, efficacy, and durability are important considerations when selecting a bioprosthesis for aortic valve replacement (AVR). This study assessed 7-year clinical outcomes and haemodynamic performance of the Avalus bioprosthesis.
Methods: Patients indicated for surgical AVR were enrolled in this prospective, nonrandomized trial, conducted across 39 sites globally.
Effects of body posture on aortic valve hemodynamics and biomechanics using the fluid-structure interaction method.
J Biomech
December 2024
School of Aeronautic Science and Engineering, Beihang University, Beijing, China.
Article Synopsis
- Bioprosthetic heart valves (BHVs) are commonly used in medicine but can suffer from fatigue damage due to their sensitivity to body positions.
- The study analyzed the effects of different postures—upright, sitting, prone, supine, and orthostatic hypotension (OH)—on the performance of these valves using a simulation model.
- Results indicated that the OH position negatively impacted valve function the most, causing increased regurgitation and flutter, which heightens the risk of thrombosis and damage; thus, patients should avoid this posture for better valve longevity.
Three-Year Outcomes Following TAVR in Younger (<75 Years) Low-Surgical-Risk Severe Aortic Stenosis Patients.
Circ Cardiovasc Interv
November 2024
Department of Interventional Cardiology and Cardiothoracic Surgery, Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, TX (N.S.K., M.J.R.).
Article Synopsis
- A study compared transcatheter aortic valve replacement (TAVR) with traditional surgery in low-risk patients under 75 years old with severe aortic stenosis to evaluate safety and effectiveness over three years.* -
- Results showed that TAVR patients had similar overall mortality rates but significantly fewer disabling strokes (0.6%) compared to surgery patients (2.9%), while TAVR also resulted in better valve performance.* -
- Both treatment options had comparable low rates of valve reinterventions, but TAVR patients experienced higher rates of pacemaker implantation (21.0% vs. 7.1%).*
Direct Oral Anticoagulants for Rheumatic Heart Disease-Associated Atrial Fibrillation Post-Bioprosthetic Mitral Valve Replacement.
JACC Clin Electrophysiol
December 2024
Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, Kentucky, USA.
Background: The efficacy of direct oral anticoagulants (DOACs) in preventing ischemic and thromboembolic events may be suboptimal in atrial fibrillation (AF) patients with rheumatic mitral stenosis. However, their safety and effectiveness after mitral valve replacement (MVR) using bioprosthetic valves is unclear.
Objectives: This study sought to evaluate the safety and effectiveness of DOACs vs warfarin among patients with rheumatic heart disease (RHD)-associated AF after bioprosthetic MVR.
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