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Interspecies transmission of canine influenza virus H5N2 to cats and chickens by close contact with experimentally infected dogs. | LitMetric

Interspecies transmission of canine influenza virus H5N2 to cats and chickens by close contact with experimentally infected dogs.

Vet Microbiol

Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, Shandong 271018, China; College of Veterinary Medicine, Shandong Agricultural University, Taian, Shandong 271018, China. Electronic address:

Published: June 2014

AI Article Synopsis

  • - The H5N2 influenza virus, isolated from a symptomatic dog in China in 2009, has been confirmed to transmit between dogs but its transmission to other species was unclear.
  • - Contact exposure experiments were conducted with susceptible cats and chickens housed near infected dogs, revealing that one cat showed clear infection and others had seroconversion, while eight chickens displayed signs of illness and two died.
  • - The results suggest that close contact with H5N2-infected dogs can lead to the virus spreading to both cats and chickens, indicating possible interspecies transmission.

Article Abstract

The novel H5N2 influenza virus, CA/SD/JT01/09, was isolated from the dog exhibiting respiratory signs in China in 2009. Dog to dog transmission of the novel H5N2 was previously confirmed. But interspecies transmission of the virus between dogs and the other animals has still remained unclear. To determine whether the virus can be transmitted directly from dogs to cats and chickens, we conducted contact exposure experiments. Susceptible cats and chickens were housed in the room which the novel H5N2 infected dogs were housed in, respectively. As a result, only one cat showed clear manifestations of H5N2 infection, but susceptibility of the other cats to H5N2 was confirmed by seroconversion. Eight of the exposure chickens showed clear manifestations of illness and 2 chickens died, and it demonstrates that chickens are susceptible to the recombinant H5N2. It implied that close contact between the H5N2-infected dogs and the cats and chickens resulted in spread of the virus to the sentinel animals.

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Source
http://dx.doi.org/10.1016/j.vetmic.2014.02.040DOI Listing

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