AI Article Synopsis
- Leprosy remains prevalent in some developing countries, like India and Brazil, caused by the bacterium Mycobacterium leprae, leading to significant health complications.
- Although sensory loss is a major symptom, chronic pain associated with leprosy is now being acknowledged as a serious late complication.
- The article explores methods to assess leprosy-related pain and suggests potential factors contributing to its persistence, as well as new treatment avenues for chronic pain management in affected individuals.
Article Abstract
Leprosy is still considered to be endemic in several developing countries, such as India and Brazil. Infection with Mycobacterium leprae leads to chronic granulomatous inflammation in skin and peripheral nerves that can lead to sensory, motor and autonomic impairments. Since the disease causes severe sensory loss, little attention has been given to pain in leprosy. However, chronic pain in leprosy is being increasingly recognized as an important late complication of leprosy. This article discusses the assessment of pain in leprosy and suggests factors that can contribute to the chronicity. We also consider pain as a multiple system output, bringing the possibility of new treatment options for chronic pain in leprosy.
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| http://dx.doi.org/10.2217/pmt.13.12 | DOI Listing |
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