Most frequent cause of abnormalities of elastic properties of walls of abdominal aorta is development of atherosclerosis resulting in replacement of elastin by simpler fibrillar proteins and collagen. This subsequently leads to dilation of the aorta and formation of aneurism. Increase of collagen content in the aortic wall correlates with growth of aneurism dimensions. Main method of treatment of aneurisms is implantation of abdominal aortic prosthesis. Detailed preoperative assessment of functional state of the aortic wall is necessary in preoperative period but none of modern imaging instrumental methods including ultrasound study allows to realize this assessment. In this article we present first experience of assessment of aortic wall deformation velocity analyzing results of ultrasound study with the help of the Multivox working station in 36 patients 16 of whom were operated because of aneurism of abdominal aorta.
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Ital J Pediatr
January 2025
Department of Neonatology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao tong University, Shanghai, China.
Background: The variety of shocks in neonates, if not recognized and treated immediately, is a major cause for fatality. The use of echocardiography may improve assessment and treatment, but its reference values across gestational age (GA) and birth weight (BW) are lacking. To address the information gap, this study aimed at correlating GA and BW of newborns with nonhemodynamic abnormalities, and at evaluating the usefulness of such reference values in neonates with early onset septic (EOS) -shock.
View Article and Find Full Text PDFComput Biol Med
January 2025
Department of Mechanical Engineering, Isfahan University of Technology, Isfahan, Iran. Electronic address:
Atherogenesis is prone in medium and large-sized vessels, such as the aorta and coronary arteries, where hemodynamic stress is critical. Low and oscillatory wall shear stress contributes significantly to endothelial dysfunction and inflammation. Murray's law minimizes energy expenditure in vascular networks and applies to small arteries.
View Article and Find Full Text PDFLife Metab
February 2025
Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Institutes of Biomedical Sciences, Fudan University, Shanghai 200438, China.
Abdominal aortic aneurysm (AAA) is strongly correlated with obesity, partially due to the abnormal expansion of abdominal perivascular adipose tissue (PVAT). Cell death-inducing DNA fragmentation factor-like effector C (CIDEC), also known as fat-specific protein 27 (FSP27) in rodents, is specifically expressed in adipose tissue where it mediates lipid droplet fusion and adipose tissue expansion. Whether and how CIDEC/FSP27 plays a role in AAA pathology remains elusive.
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
April 2025
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX.
Adverse iliofemoral anatomy represents a unique challenge for endovascular aortic aneurysm repair (EVAR). This report describes a transaxillary EVAR in a patient with severe iliofemoral occlusive disease and an infrarenal aortic aneurysm. A reversely mounted Gore Excluder graft was advanced and deployed in the infrarenal aorta using the left axillary artery.
View Article and Find Full Text PDFRen Fail
December 2025
Department of Nephrology, Chengyang District People's Hospital, Qingdao, China.
Background: Vascular calcification is common and progressive in patients with chronic kidney disease. However, the risk factors associated with the progression of vascular calcification in patients receiving maintenance dialysis have not been fully elucidated. Here, we aimed to evaluate vascular calcification and identify the factors associated with its progression in patients receiving maintenance hemodialysis.
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