Evaluation of Zn affinity for the amyloid-β peptide involved in Alzheimer's disease and its modified counterparts is reported. This was made possible by the use of a new water-soluble chelator, the properties of which have also been described. Changes in the peptide sequence that impact Zn affinity are briefly discussed.
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http://dx.doi.org/10.1039/c4mt00016a | DOI Listing |
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