As newer anesthesia ventilators are developed their capabilities are becoming more similar to intensive care unit (ICU) ventilators. However, in situations where there is severe decrease in lung compliance, an ICU ventilator may be superior in its ability to regulate inspiratory flow improving both ventilation and oxygenation. We present a case where an ICU ventilator was brought to the operating room and used in the treatment of ARDS post-cardiopulmonary bypass and ultimately allowed us to avoid extracorporeal membrane oxygenation (ECMO) therapy.
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Interdiscip Cardiovasc Thorac Surg
December 2024
Department Cardiothoracic Surgery, Gold Coast University Hospital, Southport, QLD, Australia.
Objectives: A best evidence topic was written according to a structured protocol described in ICVTS. The question addressed was 'In patients with vasoplegic syndrome following cardiac surgery with cardiopulmonary bypass, does adjunctive methylene blue improve outcomes including reduced mortality, morbidity and vasopressor requirements?'
Methods: Ovid Medline was searched using a reported search algorithm. Articles that represented the best evidence to answer the clinical question were selected, tabulated and discussed.
Anaesth Intensive Care
November 2024
Child Health Research Centre, The University of Queensland, Brisbane, Australia.
Renal chloride metabolism is currently poorly understood but may serve as both a diagnostic and a treatment approach for acute kidney injury. We investigated whether plasma chloride, ammonia and glutamine as well as urinary chloride, ammonium and glutamine concentrations may serve as markers for acute kidney injury in paediatric patients. We conducted a prospective observational trial in a tertiary care paediatric intensive care unit.
View Article and Find Full Text PDFPaediatr Anaesth
December 2024
Department of Pediatric and Congenital Heart Surgery, Pediatric Heart Centre, University Hospital Giessen and Marburg GmbH, Giessen, Germany.
Background: Patients with hypoplastic left heart syndrome undergo the comprehensive stage 2 procedure as the second stage in the hybrid approach toward Fontan circulation. The complexity of comprehensive stage 2 procedure is considered a potential limitation, and limited information is available on its anesthetic management. This study aims to address this gap.
View Article and Find Full Text PDFCommun Biol
August 2024
Key Laboratory of Organ Regeneration and Reconstruction, State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
The kidney is vulnerable to ischemia and reperfusion (I/R) injury that can be fatal after major surgery. Currently, there are no effective treatments for I/R-induced kidney injury. Trimethylamine N-oxide (TMAO) is a gut-derived metabolite linked to many diseases, but its role in I/R-induced kidney injury remains unclear.
View Article and Find Full Text PDFBMJ Open
August 2024
Department of Anesthesiology, The University of Oklahama Health Sciences Centre, Oklahoma City, Oklahoma, USA.
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