The efficacy of a 1.5% reamberin solution possessing detoxicating, antihypoxant, antioxidant, and membrane-protective properties, used as a component of the complex infusion therapy in children with acute Epstein-Barr virus infection, has been estimated. The dynamics of the inflammatory process in children treated by the drug complex including reamberin is characterized by rapid relief of general symptoms, improvement of state, and reduction in length of the febrile period of disease as compared to patients treated with glucose-saline solutions and basic therapy. The administration of reamberin in children contributed to the early elimination of metabolic shifts by the period of convalescence, as evidenced by improvement in some laboratory parameters, including protein-synthesis function of the liver.
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Blood Adv
February 2025
Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA.
Little is known about the impact of recent advances in acute myeloid leukemia (AML) treatment on racial/ethnic disparities in survival outcomes. We performed a retrospective cohort study of patients with newly diagnosed AML using data from a nationwide electronic health record-derived deidentified database. Patients were categorized based on their diagnosis date relative to venetoclax approval, as pre-novel therapy era (Pre era; 2014-2018; n = 2998) or post-novel therapy era (Post era; 2019-2022; n = 2098).
View Article and Find Full Text PDFIndian J Pediatr
January 2025
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Objectives: To compare six doses of intrapleural streptokinase (SK) vs. the conventional three doses in children with empyema.
Methods: In this randomized controlled trial, children with empyema received intrapleural streptokinase, either twice daily for 3 d (total 6 doses); or once daily for 3 d (total 3 doses).
Eur Arch Paediatr Dent
January 2025
Department of Paediatric Dentistry, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
Purpose: Assess the knowledge and attitudes of parents/guardians regarding their children's oral health and their preferences regarding the treatment of carious primary teeth.
Methods: A cross-sectional study including the completion of a questionnaire by parents/guardians of healthy children aged 2-12 years attending the Department of Pediatric Dentistry (NKUA). Data were collected through 35 questions regarding demographic characteristics of the participants, oral hygiene and dietary habits, and parents' knowledge of the importance of oral health and primary teeth.
Acta Neurochir (Wien)
January 2025
Department of Neurosurgery, LMU University Hospital, Ludwig-Maximilians-University Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Purpose: Treatment strategies for space-occupying/symptomatic pineal cysts (PC) are still up for debate. In this study we present PC management, outcome data and risk factors for recurrence after surgery, focusing on microscopic/endoscopic procedures vs. stereotactic catheter implantation as alternative treatment concept to permanently drain PC into ventricles/cisterns.
View Article and Find Full Text PDFPediatr Nephrol
January 2025
Pediatric Nephrology Services, Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.
Background: Information on the clinical characteristics and outcomes of children undergoing continuous kidney replacement therapy (CKRT) from lower-middle-income countries (LMIC) is limited.
Methods: Records of consecutive children 1 month to 18 years of age who underwent CKRT from Jan 2016 to Jan 2024 in a tertiary care pediatric intensive care unit (PICU) were retrospectively reviewed and analyzed for clinical and machine-related characteristics, and outcomes.
Results: Over the 8-year period, 102 patients (61.
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