AI Article Synopsis
- A fifth case of oculomasticatory myorhythmia linked to cerebral Whipple's disease is documented, showing unique rhythmic eye and muscle movements not seen with other brain disorders.
- These involuntary movements, which started 13 years after the disease began, persisted until the patient's death three months later, despite various treatments failing to alleviate them.
- Associated symptoms included difficulty with eye movement, facial weakness, drooping eyelids, a lack of gag reflex, and a decline in cognitive abilities.
Article Abstract
A fifth case of oculomasticatory myorhythmia associated with cerebral Whipple's disease is reported. This peculiar abnormal movement has never been described in association with cerebral dysfunction other than Whipple's disease. The present case exhibited rhythmic convergence of the eyes and synchronous (1-2 Hz) contractions of the masticatory muscles and of the proximal and distal skeletal muscles. These abnormal movements occurred 13 years after the beginning of the disease. They were persistent and unchanged until the death of the patient 3 months later. No treatment was effective to suppress the involuntary movements (clonazepam, baclofen, antibiotics). Associated neurological signs included global supranuclear ophthalmoplegia, facial weakness, bilateral ptosis, absent gag reflex, and intellectual deterioration.
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| http://dx.doi.org/10.1002/mds.870030211 | DOI Listing |
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