This study assesses lateral tipping motion-induced interruptions (MIIs) in a simulated motion environment. The objective is to revisit MII occurrence and sway motion relationship by focusing on the frequency and acceleration of the lateral motion stimulus. Results verify that MIIs increase with increasing peak sway acceleration, but the effect of sway frequency is not as clear as that of acceleration. Complex multidirectional motions create more tipping MIIs than unidirectional motion. Research should incorporate acceleration, frequency and motion complexity as factors influencing MII occurrence. To describe a temporary loss of balance without tipping, the term 'probable' MII is introduced. This term fills the gap between the theoretical definition and a human-centred perception of an MII where loss of balance is not a binary phenomenon. The 'probable' MIIs were 16-67% more common than the 'definite' MIIs. The developed mathematical model of MII occurrence versus sway acceleration (amplitude, frequency) approximated the observed MIIs with less than 9% difference.
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http://dx.doi.org/10.1080/00140139.2014.897373 | DOI Listing |
World J Gastroenterol
December 2024
School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Background: Diagnosing laryngopharyngeal reflux (LPR) is challenging due to overlapping symptoms. While proton pump inhibitors (PPIs) are commonly prescribed, reliable predictors of their responsiveness are unclear. Reflux monitoring technologies like dual potential of hydrogen (pH) sensors and multichannel intraluminal impedance-pH (MII-pH) could improve diagnosis.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Laboratory of Medical Genetics and Human Reproduction, School of Health Sciences, Faculty of Medicine, University of Ioannina, 451 10 Ioannina, Greece.
Retrotransposable elements are implicated in genome rearrangements and gene expression alterations that result in various human disorders. In the current study, we sought to investigate the potential effects of long interspersed elements-1 (LINE-1) overexpression on the integrity and methylation of DNA and on the expression of three major pluripotency factors (OCT4, SOX2, NANOG) during the preimplantation stages of human embryo development. Human MI oocytes were matured in vitro to MII and transfected through intracytoplasmic sperm injection (ICSI) either with an EGFP vector carrying a cloned active human LINE-1 retroelement or with the same EGFP vector without insert as control.
View Article and Find Full Text PDFRisk Manag Healthc Policy
November 2024
Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Enshi, Hubei Province, People's Republic of China.
Background: Coronary heart disease (CHD) is a leading cause of mortality worldwide, with atrial fibrillation (AF) being a common complication. Chronic inflammatory responses play a significant role in the relationship between coronary artery disease and AF. This study aims to investigate the value of the multi-inflammatory index (MII) in predicting the occurrence of atrial fibrillation in patients with coronary heart disease.
View Article and Find Full Text PDFJ Assist Reprod Genet
December 2024
Reproductive Medicine Center, Maternal and Child Health Care Hospital of Yulin, No. 290, Qingning Road, Yulin Guangxi, 537000, China.
Background: The DuoStim protocol has been proposed as an alternative to conventional single and double stimulation cycles in the treatment of infertility. However, its efficacy in improving pregnancy outcomes remains uncertain.
Objective: To systematically evaluate the impact of the DuoStim protocol on pregnancy outcomes in infertile patients by comparing it with single and double conventional stimulation cycles.
J Assist Reprod Genet
December 2024
Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Haidian District, 49 Huayuan North Road, Beijing, People's Republic of China.
Purpose: To evaluate the difference in the number of euploid blastocysts and cumulative live birth rate (LBR) between dual and human chorionic gonadotropin (hCG) triggers in poor and normal ovarian responders undergoing preimplantation genetic testing (PGT) cycles.
Methods: This retrospective cohort study was enrolled from July 2018 to December 2021 and followed up until June 2024 at a single reproductive medical center. Overall, 1040 in vitro fertilization (IVF)-PGT and 784 frozen-thawed embryo transfer (FET) cycles were assessed.
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