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Ten tips in lupus nephritis management.
Clin Kidney J
January 2025
Division of Nephrology, School of Clinical Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR.
Lupus nephritis is an important cause of severe glomerulonephritis, and a leading cause of kidney failure in young adults. While the disease can lead to rapid destruction of nephrons if untreated, there are effective therapies to reverse the severe acute kidney injury and prevent the lifetime risk of kidney failure. Early diagnosis and timely intervention are therefore of critical importance.
View Article and Find Full Text PDFOptogenetics has transformed the study of neural circuit function, but limitations in its application to species with large brains, such as non-human primates (NHPs), remain. A major challenge in NHP optogenetics is delivering light to sufficiently large volumes of deep neural tissue with high spatiotemporal precision, without simultaneously affecting superficial tissue. To overcome these limitations, we recently developed and tested in NHP cortex, the Utah Optrode Array (UOA).
View Article and Find Full Text PDFA NiP/NiMoO nanocone electrocatalyst for efficient hydrogen evolution: tip-enhanced local electric field effect.
Nanoscale
January 2025
College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, China.
The sluggish kinetics of the hydrogen evolution reaction (HER) result in a high overpotential in alkaline solutions. A high-curvature metal oxide heterostructure can effectively boost the electrocatalytic HER by leveraging the tip-enhanced local electric field effect. Herein, NiP/NiMoO nanocones were synthesised on a nickel foam (NF) substrate by etching a metal-organic framework template.
View Article and Find Full Text PDF"I wanna know what to expect" - Care needs regarding sexual and reproductive health after cancer in adolescence and young adulthood (AYA) and recommendations for providers.
Eur J Oncol Nurs
January 2025
Department of Medical and Clinical Psychology, Center of Research on Psychological and Somatic Disorders, Tilburg University, Tilburg, the Netherlands.
Purpose: To assess care needs related to sexual and reproductive health of patients and survivors diagnosed with cancer during adolescence and young adulthood (AYA).
Methods: Participants (N = 190) were predominantly female (87.4%) and diagnosed with cancer between age 12-39 years.
An involvement of a new zinc finger protein PbrZFP719 into pear self-incompatibility reaction.
Plant Cell Rep
January 2025
State Key Laboratory of Crop Genetics and Germplasm Enhancement, Saya Institute of Nanjing Agricultural University, Nanjing Agricultural University, Nanjing, 211800, China.
This study indicated that the CCHC-type zinc finger protein PbrZFP719 involves into self-incompatibility by affecting the levels of reactive oxygen species and cellulose content at the tips of pollen tubes. S-RNase-based self-incompatibility (SI) facilitates cross-pollination and prevents self-pollination, which in turn increases the costs associated with artificial pollination in fruit crops. Self S-RNase exerts its inhibitory effects on pollen tube growth by altering cell structures and components, including reactive oxygen species (ROS) level and cellulose content.
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