Objective: To compare and contrast the characteristics of 2 groups of men ≥40 years old: reported anabolic-androgenic steroid (AAS) users and nonusers.
Design: Cross-sectional survey.
Setting: Thirty-eight online fitness, weight lifting, bodybuilding, and steroid Web sites.
Participants: A total of 67 male AAS users and 76 male nonusers ≥40 years old.
Main Outcomes Measured: Demographics, utilization of AAS and other performance-enhancing agents (PEAs), exercise patterns, history of illicit drugs and alcohol use, and psychiatric traits/diagnoses.
Results: The majority of AAS users ≥40 years old were caucasian (92.5%), heterosexual (97.0%), and classified themselves as recreational exercisers (79.1%). AAS users took more PEAs (11.5 ± 5.6 vs 4.6 ± 2.7; P < .001), were more likely to binge drink (47.8% vs 29.0%; P = .025), report heavy alcohol use (21.0% vs 7.9%; P = .031), meet criteria for substance dependence disorder (27.4% vs 4.0%; P < .001), and report an anxiety disorder diagnosis (12.0% vs 2.6%; P = .046) than nonusers.
Conclusions: AAS misuse is prevalent among older men and is associated with polypharmacy, more aggressive alcohol use, and a higher incidence of substance dependence and anxiety disorders compared to nonusers. This information may help clinicians and researchers identify and develop appropriate intervention strategies for AAS abuse among older men.
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http://dx.doi.org/10.1177/0897190014527319 | DOI Listing |
Toxicol Appl Pharmacol
January 2025
iNOVA4HEALTH, NOVA Medical School, Faculdade de Ciências Médicas (NMS/FCM), Universidade Nova de Lisboa, 1159-056 Lisboa, Portugal; Department of Physiological Sciences, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
Millions of individuals make illicit use of anabolic-androgenic steroids (AAS), remaining a public health issue. It often leads to detrimental effects, including cardiovascular and renal diseases, besides hormonal and metabolic imbalances. The objective of this review is to emphasize the contribution of oxidative stress and inflammation to these effects and connect the findings of experimental animal studies with the alterations found in clinical contexts, in AAS users.
View Article and Find Full Text PDFJ Natl Med Assoc
December 2024
Department of Community Health and Preventive Medicine, Morehouse School of Medicine, 720 Westview Drive SW., Atlanta, GA 30310, USA.
Objectives: This study investigates the association between statin use and all-cause mortality, as well as the association between statin use and incident diabetes or prediabetes among African Americans.
Methods: This study is based on the Jackson Heart Study (JHS), a community-based cohort study of African Americans (AAs). The baseline period for JHS was 9/26/2000 to 3/31/2004.
Cureus
October 2024
Internal Medicine, Sound Physicians/Montefiore Nyack Hospital, Nyack, USA.
Purpose: To evaluate the risk of incidence rates of uveitis among patients starting topical glaucoma therapy.
Design: Retrospective database study utilizing the Sight Outcomes Research Collaborative (SOURCE) Ophthalmology Data Repository.
Participants: Adult glaucoma patients who were recently started on topical glaucoma therapy.
Arthrosc Sports Med Rehabil
October 2024
Graduate Entry Medical School, University of Limerick, Limerick, Ireland.
Purpose: To compare the characteristics of the top-20 studies about anterior shoulder instability according to the Altmetric Attention Score (AAS) with total citation counts.
Methods: Two separate searches were performed for articles related to anterior shoulder instability. The Altmetric search identified the top-20 articles according to AAS.
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