Some organic compounds gelate liquids by forming a network of anisotropic fibres. Hansen solubility parameters can be used to predict the range of liquids that are likely to be gelled by any given gelator. We critically review the various approaches recently proposed in the literature. In particular, we discuss the shape of the gelation domain, the relevance of the Teas plot representation and the use of group contribution calculations. We also propose an improved scheme for the solubility tests, and a detailed procedure for the determination of the gelation domain.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c4sm00244j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
High-Performance Porous Supports Based on Hydroxyl-Terminated Polysulfone and CO/CO-Selective Composite Membranes.
Polymers (Basel)
December 2024
Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1, 119991 Moscow, Russia.
The scope of this work was to develop a thin-film composite (TFC) membrane for the separation of CO/CO mixtures, which are relevant for many processes of gas processing and gasification of carbon-based feedstock. Special attention was given to the development of highly permeable porous polysulfone (PSF) supports (more than 26,000 GPU for CO) since both the selective and support layers contribute significantly to the overall performance of the TFC membrane. The PSF porous support is widely used in commercial and lab-scale TFC membranes, and its porous structure and other exploitation parameters are set during the non-solvent-induced phase separation (NIPS) process.
View Article and Find Full Text PDFUnveiling the potential of pullulan in enhancing ketoprofen release from PHBV filaments.
Int J Biol Macromol
January 2025
Chemical Engineering Department, Engineering School of Lorena, University of São Paulo, Lorena, São Paulo, Brazil. Electronic address:
In this study, sustainable poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and pullulan (PUL)/PHBV filaments were prepared with ketoprofen for scaffold preparation. The research aimed evaluate the influence of pullulan in the filament properties, such as thermal, morphological, and biological behavior. Hansen parameters demonstrated the difference in the miscibility of the polymers and drug in the blend.
View Article and Find Full Text PDFHigh drug-loaded amorphous solid dispersions of a poor glass forming drug: The impact of polymer type and cooling rate on amorphous drug behaviour.
Int J Pharm
December 2024
Pharmaceutical Engineering Group, Medical Biology Centre, 97, Lisburn Road, Belfast BT9 7BL, Northern Ireland, United Kingdom. Electronic address:
Enhancing the aqueous solubility via amorphization of crystalline poor glass-forming drugs represents a challenge, particularly when drug dosing is high. In such scenarios, there is often a need for high polymer loadings, leading to an increase in the dosage form mass and less patient acceptability. This work investigated the role that polymer type and after-melt cooling rate had upon the amorphicity of solid dispersions (SDs) containing high levels of naproxen and three commonly used polymeric excipients: Eudragit® EPO, Kollidon® VA64, and Soluplus®.
View Article and Find Full Text PDFAssessment of CPME as Sustainable Low VOC Alternative to Hexane: Optimization of Extraction Efficiency and Bioactive Compound Yield from Fenugreek Seed Oil Using Computational and Experimental Methods.
Foods
December 2024
Laboratory of Aromatic and Medicinal Plants, Borj Cedria Biotechnology Center, BP 901, Hammam-Lif 2050, Tunisia.
Article Synopsis
- This study explores the use of cyclopentyl methyl ether (CPME) as a more efficient and environmentally friendly alternative to hexane for extracting fenugreek seed oil.
- In simulations and experiments, CPME outperformed hexane, yielding 7.23% oil compared to hexane's 4.25% and preserving more beneficial fatty acids and bioactive compounds.
- CPME also demonstrates better oxidative stability and lower volatile organic compound emissions, making it a sustainable option for oil extraction while offering improved antioxidant and antibacterial properties.
Compartment-Resolved Proteomics with Deep Extracellular Matrix Coverage.
Bio Protoc
December 2024
Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado, Aurora, CO, USA.
The extracellular matrix (ECM) is a complex network of proteins that provides structural support and biochemical cues to cells within tissues. Characterizing ECM composition is critical for understanding this tissue component's roles in development, homeostasis, and disease processes. This protocol describes an integrated pipeline for profiling both cellular and ECM proteins across varied tissue types using mass spectrometry-based proteomics.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!