Skin reactions against injected or implanted foreign materials are not rare. Siderosis is a disease characterized by the accumulation of iron in various tissues. Brownish-gray discoloration of the skin can be seen as a side-effect on the injection area after the parenteral iron treatment. Here, we present cutaneous siderosis case developed after multiple intramuscular iron injection on the gluteal region for iron-deficiency anemia. Development of cutaneous siderosis after intramuscular iron injection rarely has been reported in the literature before.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3109/15569527.2013.875558 | DOI Listing |
Hematology Am Soc Hematol Educ Program
December 2024
Harvard Medical School, Boston, MA.
The porphyrias are a group of disorders of heme biosynthesis, each characterized by an enzymatic defect in the heme biosynthetic pathway. Porphyria cutanea tarda (PCT) arises due to the inhibition of uroporphyrinogen decarboxylase (UROD) in the presence of hepatic iron and oxidative stress. Most patients with PCT have evidence of siderosis on liver biopsy, and the disease resolves with iron depletion.
View Article and Find Full Text PDFLasers Surg Med
September 2024
Department of Dermatology, University of California, Irvine, Irvine, California, USA.
J Cosmet Dermatol
October 2024
Department of Dermatology, Soonchunhyang University Cheonan Hospital, Cheonan, South Korea.
Am J Dermatopathol
July 2023
Department of Dermatology, Serveis Mèdics Penedès, Vilanova i la Geltrú, Barcelona, Spain.
Hemosiderosis consists of an iron deposit in tissues, which does not cause organic damage to them. However, in the case of the skin, being an organ exposed to sight, siderosis can produce a brownish coloration that is aesthetically discomforting for the individual. Most cutaneous sideroses are because of venous insufficiency with hemorrhagic extravasation.
View Article and Find Full Text PDFCan J Kidney Health Dis
April 2023
Nephrology, St. Paul's Hospital, Vancouver, BC, Canada.
Rationale: Intravenous iron is commonly use in anemia related to chronic kidney disease. Skin staining due to iron extravasation is a rare adverse reaction that can leave a long-term staining of the skin.
Presenting Concerns Of The Patients: During iron derisomaltose infusion, patient reported iron extravasation.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!