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Criteria for Assessing Exposure to Biomechanical Risk Factors: A Research-to-Practice Guide-Part 2: Upper Limbs.
Life (Basel)
January 2025
Occupational Medicine Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Musculoskeletal disorders are the most prevalent occupational health problem and are often related to biomechanical risk factors. Over the last forty years, observational methods for exposure assessment have been proposed. To apply them effectively in the field, an in-depth knowledge of each methodology and a solid understanding of their actual predictive value and limitations are required.
View Article and Find Full Text PDFThe Songdo consensus: Development of minimum reporting standards for studies of intervention in idiopathic anal fistula using a modified nominal group technique.
Colorectal Dis
January 2025
Robin Phillips' Fistula Research Unit, St Mark's Hospital, London, UK.
Aim: Cryptoglandular anal fistulas carry a substantial burden to quality of life. Surgery is the only effective curative treatment but requires balancing fistula healing against pain, wounds and continence impairment. Sphincter-preserving procedures do exist but demonstrate variable rates of success.
View Article and Find Full Text PDFAssessment of Negative Symptoms in Schizophrenia: From the Consensus Conference-Derived Scales to Remote Digital Phenotyping.
Brain Sci
January 2025
Department of Mental and Physical Health and Preventive Medicine, School of Medicine, University of Campania Luigi Vanvitelli, Largo Madonna delle Grazie 1, 80135 Naples, Italy.
The assessment of negative symptoms in schizophrenia has advanced since the 2006 NIMH-MATRICS Consensus Statement, leading to the development of second-generation rating scales like the Brief Negative Symptom Scale and the Clinical Assessment Interview for Negative Symptoms. These scales address the limitations of first-generation tools, such as the inclusion of aspects that are not negative symptoms and the lack of assessment of the subject's internal experience. However, psychometric validation of these scales is still in progress, and they are not yet recommended by regulatory agencies, thus limiting their use in clinical trials and settings.
View Article and Find Full Text PDFTranslation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting.
BMC Med
January 2025
Department of Oncology, University of Oxford, Oxford, UK.
Background: The clinical translation of positron emission tomography (PET) radiotracers for cancer management presents complex challenges. We have developed consensus-based recommendations for preclinical and clinical assessment of novel and established radiotracers, applied to image different cancer types, to improve the standardisation of translational methodologies and accelerate clinical implementation.
Methods: A consensus process was developed using the RAND/UCLA Appropriateness Method (RAM) to gather insights from a multidisciplinary panel of 38 key stakeholders on the appropriateness of preclinical and clinical methodologies and stakeholder engagement for PET radiotracer translation.
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