Major improvements in perinatal care have led to increased survival after premature birth and have allowed the survival of very young and immature newborns. Bronchopulmonary dysplasia is a serious complication of prematurity and has become a developmental lung disorder, hardly preventable due to its multiple causes. The treatment serves to maintain a normal growth, reduce the respiratory workload, and prevent further complications, by trying not to interfer with postnatal lung development. Bronchopulmonary dysplasia may be associated with bronchial hyperreactivity and an obstructive bronchial pattern that may lead to frequent hospital admissions for reactive airway disease in the small child, and contribute to the persistence of chronic lung disease mainly as a new chronic obstructive pulmonary disease phenotype in adulthood.
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Introduction: Restricted fetal and neonatal growth is a known risk factor for bronchopulmonary dysplasia (BPD) in premature infants. However, the impact of nutrition and infant growth specifically on lung growth in BPD in unknown. Moreover, whether all lung growth in BPD is beneficial is unclear.
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