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Premature Calcification of Costochondral Cartilage: A Scoping Review of the Literature.
Cureus
December 2024
Family Medicine, SingHealth Polyclinics, Singapore, SGP.
Premature costochondral calcification is a rare finding occurring in young patients and is associated with metabolic and endocrinological conditions. Significant heterogeneity exists with regard to its definition and assessment. This scoping review aimed to summarize the prevalence, risk factors, etiology, evaluation, and management of patients with premature costochondral calcification.
View Article and Find Full Text PDFReforming early intervention for premature infants: insights into integrated nursing and medical care in Western China.
Front Pediatr
December 2024
Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: Premature births has imposed substantial burdens on medical resources. Consequently, a specialized team was established and a model focused on early intervention, namely the Delivery Room Intensive Care Unit (DICU) emphasizing "care, support, and treatment" was introduced and its impact on the morbidity and mortality outcomes of newborns was assessed. Additionally, we aimed to develop a nomogram model for predicting the risk of intraventricular hemorrhage (IVH) in preterm infants.
View Article and Find Full Text PDFCRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds.
Mol Oncol
January 2025
Instituto de Investigación de Enfermedades Raras, Instituto de Salud Carlos III, Madrid, Spain.
Forkhead box L2 (FOXL2) encodes a transcription factor essential for sex determination, and ovary development and maintenance. Mutations in this gene are implicated in syndromes involving premature ovarian failure and granulosa cell tumors (GCTs). This rare cancer accounts for less than 5% of diagnosed ovarian cancers and is causally associated with the FOXL2 c.
View Article and Find Full Text PDFStudy of Demographic Characteristics, Management Details and Early Life Outcomes of Indigenous Infants With Chronic Neonatal Lung Disease in North Queensland.
J Paediatr Child Health
January 2025
Department of Paediatric Medicine, Townsville University Hospital, Townsville, Queensland, Australia.
Objective: To study the demographic characteristics, risk factors, management details and clinical outcomes to 12 months corrected age in indigenous and non-indigenous infants with chronic neonatal lung disease in North Queensland.
Design: Retrospective cohort study of infants with chronic neonatal lung disease admitted to a tertiary neonatal intensive care unit in regional Queensland from January 2015 to December 2019.
Results: There were 139 infants with chronic neonatal lung disease and 425 controls.
No Vaccine, No Organ? Ethics of Vaccine Mandates for Pediatric Transplant.
Pediatr Transplant
February 2025
Departments of Health Humanities and Bioethics, Philosophy, Pediatrics, and Neurology, University of Rochester, Rochester, New York, USA.
Many transplant programs worldwide are likely to impose vaccine mandates for pediatric solid organ transplant candidates; some already do. Three potential benefits that advocates invoke to justify mandates are improved patient outcomes, efficient organ allocation, and contributions to community protection. We show that none of these benefits can justify mandates.
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