We report the first four cases of Melioidosis treated in Iceland and review the literature. Melioidosis is caused by the saprophytic Gram negative bacteria Burkholderia pseudomallei. Most disease occurs in residents of Southeast-Asia and North-Australia. The most common presentation of Melioidosis is pneumonia but as these cases demonstrate the infection has protean manifestations and B. pseudomallei can infect nearly every organ. It is important to notify the laboratory of the possibilty of Melioidosis as the bacteria can be difficult to identify and poses an infection risk to laboratory staff. Also, B. pseudomallei is resistant to many of the antibiotics normally used to treat pneumonia and due to its intracellular persistance requires prolonged therapy.
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http://dx.doi.org/10.17992/lbl.2014.02.532 | DOI Listing |
Infect Genet Evol
December 2024
University Paris-Est, Anses, Animal health laboratory, Bacterial zoonosis unit, Maisons-Alfort, France. Electronic address:
Burkholderia pseudomallei, a soil-borne bacterium that causes melioidosis, endemic in South and Southeast Asia and northern Australia, is now emerging in new regions. Since the 1990s, cases have been reported in French overseas departments, including Martinique and Guadeloupe in the Caribbean, and Reunion Island and Mayotte in the Indian Ocean, suggesting a local presence of the bacterium. Our phylogenetic analysis of 111 B.
View Article and Find Full Text PDFSouth Afr J Crit Care
July 2024
Department of Critical Care Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Background: Melioidosis cases are increasing in Southeast Asia, posing a significant challenge owing to the rising number of diabetic and immune compromised patients. Pneumonia is the most common presentation of melioidosis, while cutaneous melioidosis is rare.
Objectives: We report a case of primary cutaneous melioidosis (PCM) that eventually required intensive care unit (ICU) management.
Aust Vet J
December 2024
College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia.
Background: Melioidosis, caused by Burkholderia pseudomallei, is an important disease that is endemic in areas of northern Australia and can cause a wide range of clinical signs in people and animals. There is limited published data on the disease in marsupials.
Case Report: Two captive red-legged pademelons (Thylogale stigmatica) with collective signs of lethargy, dysphagia and bloody oral discharge were submitted for necropsy and showed variations in pathology findings ranging from multifocal abscessation in various tissues to evidence of fulminant septicaemia.
Open Forum Infect Dis
December 2024
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
Respiratory viral infection may increase infection with progressing to clinical disease (melioidosis). This data linkage study evaluated associations between melioidosis and SARS-CoV-2 or influenza. Among 160 melioidosis cases, there was no difference in risk factors, vaccine status, or disease severity between 17 with viral co-infection and 143 without.
View Article and Find Full Text PDFCurr Res Microb Sci
November 2024
Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, India.
Melioidosis is caused by percutaneous inoculation or inhalation of , predominantly among individuals with risk factors (diabetes mellitus, immunosuppression, etc.) from endemic areas of South Asia, Southeast Asia and Northern Australia. While some patients present acutely with sepsis and multi-organ failure, others present with a subacute to chronic course characterised by abscess formation.
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